lemma health

($1.50 - $4)

Get This Treatment

KEY TAKEAWAYS

Topical Vitamin B12 cream appears to be more effective than standard moisturizing creams for treating mild eczema, with studies showing a 78% improvement in symptoms compared to 33.5% with regular creams

Study Summary	Study Type	Studied Population	Results
📄 A vitamin B12 cream was compared to a standard moisturizing cream for treating mild eczema. The vitamin B12 cream reduced eczema severity by 77.6% compared to 33.5% with the standard cream after 12 weeks of use. Superiority of a vitamin B12‐barrier cream compared with standard glycerol‐petrolatum‐based emollient cream in the treatment of atopic dermatitis: A randomized, left‐to‐right comparative trial (2017)	Randomized Controlled Trial	Total Patients: 22 Severity: mild Age: not available	Vitamin B12 cream was more than twice as effective as standard moisturizer in reducing eczema severity

There may be a connection between Vitamin B12 blood levels and eczema severity - lower Vitamin B12 levels might be associated with worse eczema symptoms. Oral Vitamin B12 supplements might help improve severe eczema that's difficult to control

Study Summary	Study Type	Studied Population	Results
📄 In a case study of one patient with severe eczema, researchers found that low vitamin B12 levels were associated with worse eczema symptoms. When the patient took vitamin B12 supplements, their eczema improved significantly. Vitamin B12 and Atopic Dermatitis: Any Therapeutic Relevance For Oral Supplementation? (2020)	Case Reports	Total Patients: 1 Severity: severe Age: 18	Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Vitamin B12 has anti-inflammatory properties and can help regulate the immune system, which may explain why it helps with eczema symptoms

Study Summary	Study Type	Studied Population	Results
📄 In a case study of one patient with severe eczema, researchers found that low vitamin B12 levels were associated with worse eczema symptoms. When the patient took vitamin B12 supplements, their eczema improved significantly. Vitamin B12 and Atopic Dermatitis: Any Therapeutic Relevance For Oral Supplementation? (2020)	Case Reports	Total Patients: 1 Severity: severe Age: 18	Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Summary:

A vitamin B12 cream was compared to a standard moisturizing cream for treating mild eczema. The vitamin B12 cream reduced eczema severity by 77.6% compared to 33.5% with the standard cream after 12 weeks of use.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 22

Severity: mild

Age: not available

Results:

Vitamin B12 cream was more than twice as effective as standard moisturizer in reducing eczema severity

Summary:

In a case study of one patient with severe eczema, researchers found that low vitamin B12 levels were associated with worse eczema symptoms. When the patient took vitamin B12 supplements, their eczema improved significantly.

Study Type:

Case Reports

Studied Population:

Total Patients: 1

Severity: severe

Age: 18

Results:

Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Vitamin B12 has anti-inflammatory properties and can help regulate the immune system, which may explain why it helps with eczema symptoms

Summary:

Study Type:

Case Reports

Studied Population:

Total Patients: 1

Severity: severe

Age: 18

Results:

Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Coconut Oil

(Virgin Coconut Oil)

If you are looking for a gentle and natural moisturizer for your child that may help reduce inflammation and bacterial colonization

If you are looking for a gentle and natural moisturizer that may help reduce inflammation and bacterial colonization

Topical daily

Low

Side Effect	Affected
Skin irritation

($6.50 - $30)

Get This Treatment

KEY TAKEAWAYS

Coconut oil, when formulated with other ingredients (specifically isosorbide diesters), can significantly improve itching in people with mild-to-moderate eczema, showing about 66% improvement in itch symptoms

Study Summary	Study Type	Studied Population	Results
📄 A cream containing coconut and sunflower seed oil derivatives improved itch by 65.6% compared to 43.8% with the control cream in people with mild-to-moderate eczema. The treatment also reduced the need for steroid creams and decreased harmful bacteria on the skin. Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis. (2024)	Randomized Controlled Trial	Total Patients: 32 Severity: mild to moderate Age: 18+	Significantly better itch relief in treatment group (p=0.013)

When used in a specialized formulation, coconut oil derivatives can help reduce the need for topical steroids in eczema treatment, particularly in the early weeks of treatment

Study Summary	Study Type	Studied Population	Results
📄 A cream containing coconut and sunflower seed oil derivatives improved itch by 65.6% compared to 43.8% with the control cream in people with mild-to-moderate eczema. The treatment also reduced the need for steroid creams and decreased harmful bacteria on the skin. Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis. (2024)	Randomized Controlled Trial	Total Patients: 32 Severity: mild to moderate Age: 18+	Significantly better itch relief in treatment group (p=0.013)

Coconut oil-based treatments may help reduce harmful bacteria (Staphylococcus aureus) on the skin of eczema patients

Study Summary	Study Type	Studied Population	Results
📄 A cream containing coconut and sunflower seed oil derivatives improved itch by 65.6% compared to 43.8% with the control cream in people with mild-to-moderate eczema. The treatment also reduced the need for steroid creams and decreased harmful bacteria on the skin. Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis. (2024)	Randomized Controlled Trial	Total Patients: 32 Severity: mild to moderate Age: 18+	Significantly better itch relief in treatment group (p=0.013)

Coconut oil is one of the most commonly used traditional home remedies for eczema treatment, particularly in Indian households

Study Summary	Study Type	Studied Population	Results
📄 In a study of 150 children in India, coconut oil was the most commonly used home remedy for treating eczema/atopic dermatitis, followed by olive oil and mustard oil. The study looked at various home remedies parents used before visiting a doctor. Home remedies in different pediatric dermatoses: An observational study (2020)	Observational Study	Total Patients: 150

Summary:

A cream containing coconut and sunflower seed oil derivatives improved itch by 65.6% compared to 43.8% with the control cream in people with mild-to-moderate eczema. The treatment also reduced the need for steroid creams and decreased harmful bacteria on the skin.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 32

Severity: mild to moderate

Age: 18+

Results:

Significantly better itch relief in treatment group (p=0.013)

When used in a specialized formulation, coconut oil derivatives can help reduce the need for topical steroids in eczema treatment, particularly in the early weeks of treatment

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 32

Severity: mild to moderate

Age: 18+

Results:

Significantly better itch relief in treatment group (p=0.013)

Coconut oil-based treatments may help reduce harmful bacteria (Staphylococcus aureus) on the skin of eczema patients

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 32

Severity: mild to moderate

Age: 18+

Results:

Significantly better itch relief in treatment group (p=0.013)

Coconut oil is one of the most commonly used traditional home remedies for eczema treatment, particularly in Indian households

Summary:

In a study of 150 children in India, coconut oil was the most commonly used home remedy for treating eczema/atopic dermatitis, followed by olive oil and mustard oil. The study looked at various home remedies parents used before visiting a doctor.

Study Type:

Observational Study

Studied Population:

Total Patients: 150

Results:

Probiotics

(Lactobacillus, Bifidobacterium)

As a complementary treatment for children with moderate atopic dermatitis

As a complementary treatment alongside standard therapies

Oral daily

Low

Side Effect	Affected
No significant side effects reported

($20 - $30)

Get This Treatment

KEY TAKEAWAYS

Probiotics appear to be effective in reducing the severity of atopic dermatitis symptoms, with multiple studies showing significant improvements in SCORAD scores (a measure of eczema severity) compared to placebo

Study Summary	Study Type	Studied Population	Results
📄 A probiotic mixture helped improve eczema symptoms in children and teenagers after 12 weeks of treatment. Patients taking probiotics needed less topical steroids between weeks 6-12 of treatment compared to those taking placebo. Randomised double blind placebo controlled clinical trial to evaluate the effect of a mixture of probiotic strains on symptom severity and the use of corticosteroids in children and adolescents with atopic dermatitis. (2023)	Randomized Controlled Trial	Total Patients: 61 Severity: not available Age: 4-17 years	Patients taking probiotics had significantly better SCORAD scores compared to placebo
📄 The probiotic LGG helped improve eczema symptoms in young children when taken daily for 12 weeks. Children who took the probiotic needed less rescue medication and had better quality of life. The benefits were linked to positive changes in both gut and skin bacteria. Therapeutic effects elicited by the probiotic Lacticaseibacillus rhamnosus GG in children with atopic dermatitis. The results of the ProPAD trial (2022)	Randomized Controlled Trial	Total Patients: 100 Severity: not available Age: 6-36 months	Significant improvement in eczema severity that was maintained after treatment
📄 An 8-week treatment with probiotics (beneficial bacteria) and prebiotics improved eczema symptoms in children. The severity of eczema decreased significantly, with the percentage of children having moderate-severe disease dropping from 92.4% to 28.1%. Effect of synbiotic supplementation on children with atopic dermatitis: an observational prospective study (2018)	Observational Study	Total Patients: 320	Significant improvement in eczema severity

Probiotics may help reduce the need for topical corticosteroids in treating atopic dermatitis, potentially allowing for less steroid use

Study Summary	Study Type	Studied Population	Results
📄 A probiotic mixture helped improve eczema symptoms in children and teenagers after 12 weeks of treatment. Patients taking probiotics needed less topical steroids between weeks 6-12 of treatment compared to those taking placebo. Randomised double blind placebo controlled clinical trial to evaluate the effect of a mixture of probiotic strains on symptom severity and the use of corticosteroids in children and adolescents with atopic dermatitis. (2023)	Randomized Controlled Trial	Total Patients: 61 Severity: not available Age: 4-17 years	Patients taking probiotics had significantly better SCORAD scores compared to placebo
📄 A mixture of probiotics taken by mouth significantly improved eczema symptoms in children with moderate atopic dermatitis. Children taking probiotics needed less topical steroids to manage their condition, with an 83% improvement in symptoms compared to 24% in the placebo group. Effect of Oral Administration of a Mixture of Probiotic Strains on SCORAD Index and Use of Topical Steroids in Young Patients With Moderate Atopic Dermatitis: A Randomized Clinical Trial (2018)	Randomized Controlled Trial	Total Patients: 50 Severity: moderate Age: 4-17 years	Probiotics led to a significantly greater improvement in eczema severity compared to placebo

Probiotics appear to be safe with very few reported side effects. Most studies reported similar adverse event rates between probiotic and placebo groups

Study Summary	Study Type	Studied Population	Results
📄 The probiotic LGG helped improve eczema symptoms in young children when taken daily for 12 weeks. Children who took the probiotic needed less rescue medication and had better quality of life. The benefits were linked to positive changes in both gut and skin bacteria. Therapeutic effects elicited by the probiotic Lacticaseibacillus rhamnosus GG in children with atopic dermatitis. The results of the ProPAD trial (2022)	Randomized Controlled Trial	Total Patients: 100 Severity: not available Age: 6-36 months	Significant improvement in eczema severity that was maintained after treatment
📄 An 8-week treatment with probiotics (beneficial bacteria) and prebiotics improved eczema symptoms in children. The severity of eczema decreased significantly, with the percentage of children having moderate-severe disease dropping from 92.4% to 28.1%. Effect of synbiotic supplementation on children with atopic dermatitis: an observational prospective study (2018)	Observational Study	Total Patients: 320	Significant improvement in eczema severity

Multi-strain probiotic combinations may be more effective than single strains, and treatment duration of 8-12 weeks appears to be optimal for seeing benefits

Study Summary	Study Type	Studied Population	Results
📄 An 8-week treatment with probiotics (beneficial bacteria) and prebiotics improved eczema symptoms in children. The severity of eczema decreased significantly, with the percentage of children having moderate-severe disease dropping from 92.4% to 28.1%. Effect of synbiotic supplementation on children with atopic dermatitis: an observational prospective study (2018)	Observational Study	Total Patients: 320	Significant improvement in eczema severity
📄 Taking specific probiotics and prebiotics for 12 weeks helped improve mild eczema symptoms, including itching and skin lesions. The study suggests that these supplements might help maintain stable eczema and reduce flare-ups. Probiotics and Prebiotics Orally Assumed as Disease Modifiers for Stable Mild Atopic Dermatitis: An Italian Real-Life, Multicenter, Retrospective, Observational Study (2023)	Observational Study	Total Patients: 144 Severity: mild Age: not specified (mean age 25.1 ± 17.6 years)	All measures of eczema severity showed significant improvement after 12 weeks of probiotic treatment

Summary:

A probiotic mixture helped improve eczema symptoms in children and teenagers after 12 weeks of treatment. Patients taking probiotics needed less topical steroids between weeks 6-12 of treatment compared to those taking placebo.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 61

Severity: not available

Age: 4-17 years

Results:

Patients taking probiotics had significantly better SCORAD scores compared to placebo

Summary:

The probiotic LGG helped improve eczema symptoms in young children when taken daily for 12 weeks. Children who took the probiotic needed less rescue medication and had better quality of life. The benefits were linked to positive changes in both gut and skin bacteria.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 100

Severity: not available

Age: 6-36 months

Results:

Significant improvement in eczema severity that was maintained after treatment

Summary:

An 8-week treatment with probiotics (beneficial bacteria) and prebiotics improved eczema symptoms in children. The severity of eczema decreased significantly, with the percentage of children having moderate-severe disease dropping from 92.4% to 28.1%.

Study Type:

Observational Study

Studied Population:

Total Patients: 320

Results:

Significant improvement in eczema severity

Probiotics may help reduce the need for topical corticosteroids in treating atopic dermatitis, potentially allowing for less steroid use

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 61

Severity: not available

Age: 4-17 years

Results:

Patients taking probiotics had significantly better SCORAD scores compared to placebo

Summary:

A mixture of probiotics taken by mouth significantly improved eczema symptoms in children with moderate atopic dermatitis. Children taking probiotics needed less topical steroids to manage their condition, with an 83% improvement in symptoms compared to 24% in the placebo group.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 50

Severity: moderate

Age: 4-17 years

Results:

Probiotics led to a significantly greater improvement in eczema severity compared to placebo

Probiotics appear to be safe with very few reported side effects. Most studies reported similar adverse event rates between probiotic and placebo groups

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 100

Severity: not available

Age: 6-36 months

Results:

Significant improvement in eczema severity that was maintained after treatment

Summary:

Study Type:

Observational Study

Studied Population:

Total Patients: 320

Results:

Significant improvement in eczema severity

Multi-strain probiotic combinations may be more effective than single strains, and treatment duration of 8-12 weeks appears to be optimal for seeing benefits

Summary:

Study Type:

Observational Study

Studied Population:

Total Patients: 320

Results:

Significant improvement in eczema severity

Summary:

Taking specific probiotics and prebiotics for 12 weeks helped improve mild eczema symptoms, including itching and skin lesions. The study suggests that these supplements might help maintain stable eczema and reduce flare-ups.

Study Type:

Observational Study

Studied Population:

Total Patients: 144

Severity: mild

Age: not specified (mean age 25.1 ± 17.6 years)

Results:

All measures of eczema severity showed significant improvement after 12 weeks of probiotic treatment

HIGHEST EFFICACY IN CATEGORY

Vitamin B12 (Cobalamin)

Who is this for?:

As an add-on alongside other therapies

Effectiveness:

Side Effects:

Low

Cost:

Delivery:

Oral daily

See Evidence

Get This Treatment

KEY TAKEAWAYS

Study Summary	Study Type	Studied Population	Results
📄 A vitamin B12 cream was compared to a standard moisturizing cream for treating mild eczema. The vitamin B12 cream reduced eczema severity by 77.6% compared to 33.5% with the standard cream after 12 weeks of use. Superiority of a vitamin B12‐barrier cream compared with standard glycerol‐petrolatum‐based emollient cream in the treatment of atopic dermatitis: A randomized, left‐to‐right comparative trial (2017)	Randomized Controlled Trial	Total Patients: 22 Severity: mild Age: not available	Vitamin B12 cream was more than twice as effective as standard moisturizer in reducing eczema severity

Study Summary	Study Type	Studied Population	Results
📄 In a case study of one patient with severe eczema, researchers found that low vitamin B12 levels were associated with worse eczema symptoms. When the patient took vitamin B12 supplements, their eczema improved significantly. Vitamin B12 and Atopic Dermatitis: Any Therapeutic Relevance For Oral Supplementation? (2020)	Case Reports	Total Patients: 1 Severity: severe Age: 18	Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Vitamin B12 has anti-inflammatory properties and can help regulate the immune system, which may explain why it helps with eczema symptoms

Study Summary	Study Type	Studied Population	Results
📄 In a case study of one patient with severe eczema, researchers found that low vitamin B12 levels were associated with worse eczema symptoms. When the patient took vitamin B12 supplements, their eczema improved significantly. Vitamin B12 and Atopic Dermatitis: Any Therapeutic Relevance For Oral Supplementation? (2020)	Case Reports	Total Patients: 1 Severity: severe Age: 18	Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 22

Severity: mild

Age: not available

Results:

Vitamin B12 cream was more than twice as effective as standard moisturizer in reducing eczema severity

Summary:

Study Type:

Case Reports

Studied Population:

Total Patients: 1

Severity: severe

Age: 18

Results:

Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Vitamin B12 has anti-inflammatory properties and can help regulate the immune system, which may explain why it helps with eczema symptoms

Summary:

Study Type:

Case Reports

Studied Population:

Total Patients: 1

Severity: severe

Age: 18

Results:

Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Coconut Oil (Virgin Coconut Oil)

Who is this for?:

If you are looking for a gentle and natural moisturizer that may help reduce inflammation and bacterial colonization

If you are looking for a gentle and natural moisturizer for your child that may help reduce inflammation and bacterial colonization

Effectiveness:

Side Effects:

Low

Cost:

Delivery:

Topical as needed daily

See Evidence

Get This Treatment

KEY TAKEAWAYS

Study Summary	Study Type	Studied Population	Results
📄 A cream containing coconut and sunflower seed oil derivatives improved itch by 65.6% compared to 43.8% with the control cream in people with mild-to-moderate eczema. The treatment also reduced the need for steroid creams and decreased harmful bacteria on the skin. Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis. (2024)	Randomized Controlled Trial	Total Patients: 32 Severity: mild to moderate Age: 18+	Significantly better itch relief in treatment group (p=0.013)

When used in a specialized formulation, coconut oil derivatives can help reduce the need for topical steroids in eczema treatment, particularly in the early weeks of treatment

Study Summary	Study Type	Studied Population	Results
📄 A cream containing coconut and sunflower seed oil derivatives improved itch by 65.6% compared to 43.8% with the control cream in people with mild-to-moderate eczema. The treatment also reduced the need for steroid creams and decreased harmful bacteria on the skin. Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis. (2024)	Randomized Controlled Trial	Total Patients: 32 Severity: mild to moderate Age: 18+	Significantly better itch relief in treatment group (p=0.013)

Coconut oil-based treatments may help reduce harmful bacteria (Staphylococcus aureus) on the skin of eczema patients

Study Summary	Study Type	Studied Population	Results
📄 A cream containing coconut and sunflower seed oil derivatives improved itch by 65.6% compared to 43.8% with the control cream in people with mild-to-moderate eczema. The treatment also reduced the need for steroid creams and decreased harmful bacteria on the skin. Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis. (2024)	Randomized Controlled Trial	Total Patients: 32 Severity: mild to moderate Age: 18+	Significantly better itch relief in treatment group (p=0.013)

Coconut oil is one of the most commonly used traditional home remedies for eczema treatment, particularly in Indian households

Study Summary	Study Type	Studied Population	Results
📄 In a study of 150 children in India, coconut oil was the most commonly used home remedy for treating eczema/atopic dermatitis, followed by olive oil and mustard oil. The study looked at various home remedies parents used before visiting a doctor. Home remedies in different pediatric dermatoses: An observational study (2020)	Observational Study	Total Patients: 150

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 32

Severity: mild to moderate

Age: 18+

Results:

Significantly better itch relief in treatment group (p=0.013)

When used in a specialized formulation, coconut oil derivatives can help reduce the need for topical steroids in eczema treatment, particularly in the early weeks of treatment

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 32

Severity: mild to moderate

Age: 18+

Results:

Significantly better itch relief in treatment group (p=0.013)

Coconut oil-based treatments may help reduce harmful bacteria (Staphylococcus aureus) on the skin of eczema patients

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 32

Severity: mild to moderate

Age: 18+

Results:

Significantly better itch relief in treatment group (p=0.013)

Coconut oil is one of the most commonly used traditional home remedies for eczema treatment, particularly in Indian households

Summary:

Study Type:

Observational Study

Studied Population:

Total Patients: 150

Results:

Probiotics (Lactobacillus, Bifidobacterium)

Who is this for?:

As a complementary treatment alongside standard therapies

As a complementary treatment for children with moderate atopic dermatitis

Effectiveness:

Side Effects:

Low

Cost:

Delivery:

Oral daily

See Evidence

Get This Treatment

KEY TAKEAWAYS

Study Summary	Study Type	Studied Population	Results
📄 A probiotic mixture helped improve eczema symptoms in children and teenagers after 12 weeks of treatment. Patients taking probiotics needed less topical steroids between weeks 6-12 of treatment compared to those taking placebo. Randomised double blind placebo controlled clinical trial to evaluate the effect of a mixture of probiotic strains on symptom severity and the use of corticosteroids in children and adolescents with atopic dermatitis. (2023)	Randomized Controlled Trial	Total Patients: 61 Severity: not available Age: 4-17 years	Patients taking probiotics had significantly better SCORAD scores compared to placebo
📄 The probiotic LGG helped improve eczema symptoms in young children when taken daily for 12 weeks. Children who took the probiotic needed less rescue medication and had better quality of life. The benefits were linked to positive changes in both gut and skin bacteria. Therapeutic effects elicited by the probiotic Lacticaseibacillus rhamnosus GG in children with atopic dermatitis. The results of the ProPAD trial (2022)	Randomized Controlled Trial	Total Patients: 100 Severity: not available Age: 6-36 months	Significant improvement in eczema severity that was maintained after treatment
📄 An 8-week treatment with probiotics (beneficial bacteria) and prebiotics improved eczema symptoms in children. The severity of eczema decreased significantly, with the percentage of children having moderate-severe disease dropping from 92.4% to 28.1%. Effect of synbiotic supplementation on children with atopic dermatitis: an observational prospective study (2018)	Observational Study	Total Patients: 320	Significant improvement in eczema severity

Probiotics may help reduce the need for topical corticosteroids in treating atopic dermatitis, potentially allowing for less steroid use

Study Summary	Study Type	Studied Population	Results
📄 A probiotic mixture helped improve eczema symptoms in children and teenagers after 12 weeks of treatment. Patients taking probiotics needed less topical steroids between weeks 6-12 of treatment compared to those taking placebo. Randomised double blind placebo controlled clinical trial to evaluate the effect of a mixture of probiotic strains on symptom severity and the use of corticosteroids in children and adolescents with atopic dermatitis. (2023)	Randomized Controlled Trial	Total Patients: 61 Severity: not available Age: 4-17 years	Patients taking probiotics had significantly better SCORAD scores compared to placebo
📄 A mixture of probiotics taken by mouth significantly improved eczema symptoms in children with moderate atopic dermatitis. Children taking probiotics needed less topical steroids to manage their condition, with an 83% improvement in symptoms compared to 24% in the placebo group. Effect of Oral Administration of a Mixture of Probiotic Strains on SCORAD Index and Use of Topical Steroids in Young Patients With Moderate Atopic Dermatitis: A Randomized Clinical Trial (2018)	Randomized Controlled Trial	Total Patients: 50 Severity: moderate Age: 4-17 years	Probiotics led to a significantly greater improvement in eczema severity compared to placebo

Probiotics appear to be safe with very few reported side effects. Most studies reported similar adverse event rates between probiotic and placebo groups

Study Summary	Study Type	Studied Population	Results
📄 The probiotic LGG helped improve eczema symptoms in young children when taken daily for 12 weeks. Children who took the probiotic needed less rescue medication and had better quality of life. The benefits were linked to positive changes in both gut and skin bacteria. Therapeutic effects elicited by the probiotic Lacticaseibacillus rhamnosus GG in children with atopic dermatitis. The results of the ProPAD trial (2022)	Randomized Controlled Trial	Total Patients: 100 Severity: not available Age: 6-36 months	Significant improvement in eczema severity that was maintained after treatment
📄 An 8-week treatment with probiotics (beneficial bacteria) and prebiotics improved eczema symptoms in children. The severity of eczema decreased significantly, with the percentage of children having moderate-severe disease dropping from 92.4% to 28.1%. Effect of synbiotic supplementation on children with atopic dermatitis: an observational prospective study (2018)	Observational Study	Total Patients: 320	Significant improvement in eczema severity

Multi-strain probiotic combinations may be more effective than single strains, and treatment duration of 8-12 weeks appears to be optimal for seeing benefits

Study Summary	Study Type	Studied Population	Results
📄 An 8-week treatment with probiotics (beneficial bacteria) and prebiotics improved eczema symptoms in children. The severity of eczema decreased significantly, with the percentage of children having moderate-severe disease dropping from 92.4% to 28.1%. Effect of synbiotic supplementation on children with atopic dermatitis: an observational prospective study (2018)	Observational Study	Total Patients: 320	Significant improvement in eczema severity
📄 Taking specific probiotics and prebiotics for 12 weeks helped improve mild eczema symptoms, including itching and skin lesions. The study suggests that these supplements might help maintain stable eczema and reduce flare-ups. Probiotics and Prebiotics Orally Assumed as Disease Modifiers for Stable Mild Atopic Dermatitis: An Italian Real-Life, Multicenter, Retrospective, Observational Study (2023)	Observational Study	Total Patients: 144 Severity: mild Age: not specified (mean age 25.1 ± 17.6 years)	All measures of eczema severity showed significant improvement after 12 weeks of probiotic treatment

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 61

Severity: not available

Age: 4-17 years

Results:

Patients taking probiotics had significantly better SCORAD scores compared to placebo

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 100

Severity: not available

Age: 6-36 months

Results:

Significant improvement in eczema severity that was maintained after treatment

Summary:

Study Type:

Observational Study

Studied Population:

Total Patients: 320

Results:

Significant improvement in eczema severity

Probiotics may help reduce the need for topical corticosteroids in treating atopic dermatitis, potentially allowing for less steroid use

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 61

Severity: not available

Age: 4-17 years

Results:

Patients taking probiotics had significantly better SCORAD scores compared to placebo

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 50

Severity: moderate

Age: 4-17 years

Results:

Probiotics led to a significantly greater improvement in eczema severity compared to placebo

Probiotics appear to be safe with very few reported side effects. Most studies reported similar adverse event rates between probiotic and placebo groups

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 100

Severity: not available

Age: 6-36 months

Results:

Significant improvement in eczema severity that was maintained after treatment

Summary:

Study Type:

Observational Study

Studied Population:

Total Patients: 320

Results:

Significant improvement in eczema severity

Multi-strain probiotic combinations may be more effective than single strains, and treatment duration of 8-12 weeks appears to be optimal for seeing benefits

Summary:

Study Type:

Observational Study

Studied Population:

Total Patients: 320

Results:

Significant improvement in eczema severity

Summary:

Study Type:

Observational Study

Studied Population:

Total Patients: 144

Severity: mild

Age: not specified (mean age 25.1 ± 17.6 years)

Results:

All measures of eczema severity showed significant improvement after 12 weeks of probiotic treatment

All Supplements and Natural Remedies Treatments

Treatment

Who is this for?

Delivery

Effectiveness

Side Effects

Estimated Cost

HIGHEST EFFICACY IN CATEGORY

Vitamin B12

(Cobalamin)

As an add-on alongside other therapies

Oral daily

Low

($1.50 - $4)

Get This Treatment

KEY TAKEAWAYS

Study Summary	Study Type	Studied Population	Results
📄 A vitamin B12 cream was compared to a standard moisturizing cream for treating mild eczema. The vitamin B12 cream reduced eczema severity by 77.6% compared to 33.5% with the standard cream after 12 weeks of use. Superiority of a vitamin B12‐barrier cream compared with standard glycerol‐petrolatum‐based emollient cream in the treatment of atopic dermatitis: A randomized, left‐to‐right comparative trial (2017)	Randomized Controlled Trial	Total Patients: 22 Severity: mild Age: not available	Vitamin B12 cream was more than twice as effective as standard moisturizer in reducing eczema severity

Study Summary	Study Type	Studied Population	Results
📄 In a case study of one patient with severe eczema, researchers found that low vitamin B12 levels were associated with worse eczema symptoms. When the patient took vitamin B12 supplements, their eczema improved significantly. Vitamin B12 and Atopic Dermatitis: Any Therapeutic Relevance For Oral Supplementation? (2020)	Case Reports	Total Patients: 1 Severity: severe Age: 18	Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Vitamin B12 has anti-inflammatory properties and can help regulate the immune system, which may explain why it helps with eczema symptoms

Study Summary	Study Type	Studied Population	Results
📄 In a case study of one patient with severe eczema, researchers found that low vitamin B12 levels were associated with worse eczema symptoms. When the patient took vitamin B12 supplements, their eczema improved significantly. Vitamin B12 and Atopic Dermatitis: Any Therapeutic Relevance For Oral Supplementation? (2020)	Case Reports	Total Patients: 1 Severity: severe Age: 18	Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 22

Severity: mild

Age: not available

Results:

Vitamin B12 cream was more than twice as effective as standard moisturizer in reducing eczema severity

Summary:

Study Type:

Case Reports

Studied Population:

Total Patients: 1

Severity: severe

Age: 18

Results:

Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Vitamin B12 has anti-inflammatory properties and can help regulate the immune system, which may explain why it helps with eczema symptoms

Summary:

Study Type:

Case Reports

Studied Population:

Total Patients: 1

Severity: severe

Age: 18

Results:

Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Coconut Oil

(Virgin Coconut Oil)

If you are looking for a gentle and natural moisturizer for your child that may help reduce inflammation and bacterial colonization

If you are looking for a gentle and natural moisturizer that may help reduce inflammation and bacterial colonization

Topical daily

Low

Side Effect	Affected
Skin irritation

($6.50 - $30)

Get This Treatment

KEY TAKEAWAYS

Study Summary	Study Type	Studied Population	Results
📄 A cream containing coconut and sunflower seed oil derivatives improved itch by 65.6% compared to 43.8% with the control cream in people with mild-to-moderate eczema. The treatment also reduced the need for steroid creams and decreased harmful bacteria on the skin. Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis. (2024)	Randomized Controlled Trial	Total Patients: 32 Severity: mild to moderate Age: 18+	Significantly better itch relief in treatment group (p=0.013)

When used in a specialized formulation, coconut oil derivatives can help reduce the need for topical steroids in eczema treatment, particularly in the early weeks of treatment

Study Summary	Study Type	Studied Population	Results
📄 A cream containing coconut and sunflower seed oil derivatives improved itch by 65.6% compared to 43.8% with the control cream in people with mild-to-moderate eczema. The treatment also reduced the need for steroid creams and decreased harmful bacteria on the skin. Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis. (2024)	Randomized Controlled Trial	Total Patients: 32 Severity: mild to moderate Age: 18+	Significantly better itch relief in treatment group (p=0.013)

Coconut oil-based treatments may help reduce harmful bacteria (Staphylococcus aureus) on the skin of eczema patients

Study Summary	Study Type	Studied Population	Results
📄 A cream containing coconut and sunflower seed oil derivatives improved itch by 65.6% compared to 43.8% with the control cream in people with mild-to-moderate eczema. The treatment also reduced the need for steroid creams and decreased harmful bacteria on the skin. Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis. (2024)	Randomized Controlled Trial	Total Patients: 32 Severity: mild to moderate Age: 18+	Significantly better itch relief in treatment group (p=0.013)

Coconut oil is one of the most commonly used traditional home remedies for eczema treatment, particularly in Indian households

Study Summary	Study Type	Studied Population	Results
📄 In a study of 150 children in India, coconut oil was the most commonly used home remedy for treating eczema/atopic dermatitis, followed by olive oil and mustard oil. The study looked at various home remedies parents used before visiting a doctor. Home remedies in different pediatric dermatoses: An observational study (2020)	Observational Study	Total Patients: 150

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 32

Severity: mild to moderate

Age: 18+

Results:

Significantly better itch relief in treatment group (p=0.013)

When used in a specialized formulation, coconut oil derivatives can help reduce the need for topical steroids in eczema treatment, particularly in the early weeks of treatment

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 32

Severity: mild to moderate

Age: 18+

Results:

Significantly better itch relief in treatment group (p=0.013)

Coconut oil-based treatments may help reduce harmful bacteria (Staphylococcus aureus) on the skin of eczema patients

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 32

Severity: mild to moderate

Age: 18+

Results:

Significantly better itch relief in treatment group (p=0.013)

Coconut oil is one of the most commonly used traditional home remedies for eczema treatment, particularly in Indian households

Summary:

Study Type:

Observational Study

Studied Population:

Total Patients: 150

Results:

Probiotics

(Lactobacillus, Bifidobacterium)

As a complementary treatment for children with moderate atopic dermatitis

As a complementary treatment alongside standard therapies

Oral daily

Low

Side Effect	Affected
No significant side effects reported

($20 - $30)

Get This Treatment

KEY TAKEAWAYS

Study Summary	Study Type	Studied Population	Results
📄 A probiotic mixture helped improve eczema symptoms in children and teenagers after 12 weeks of treatment. Patients taking probiotics needed less topical steroids between weeks 6-12 of treatment compared to those taking placebo. Randomised double blind placebo controlled clinical trial to evaluate the effect of a mixture of probiotic strains on symptom severity and the use of corticosteroids in children and adolescents with atopic dermatitis. (2023)	Randomized Controlled Trial	Total Patients: 61 Severity: not available Age: 4-17 years	Patients taking probiotics had significantly better SCORAD scores compared to placebo
📄 The probiotic LGG helped improve eczema symptoms in young children when taken daily for 12 weeks. Children who took the probiotic needed less rescue medication and had better quality of life. The benefits were linked to positive changes in both gut and skin bacteria. Therapeutic effects elicited by the probiotic Lacticaseibacillus rhamnosus GG in children with atopic dermatitis. The results of the ProPAD trial (2022)	Randomized Controlled Trial	Total Patients: 100 Severity: not available Age: 6-36 months	Significant improvement in eczema severity that was maintained after treatment
📄 An 8-week treatment with probiotics (beneficial bacteria) and prebiotics improved eczema symptoms in children. The severity of eczema decreased significantly, with the percentage of children having moderate-severe disease dropping from 92.4% to 28.1%. Effect of synbiotic supplementation on children with atopic dermatitis: an observational prospective study (2018)	Observational Study	Total Patients: 320	Significant improvement in eczema severity

Probiotics may help reduce the need for topical corticosteroids in treating atopic dermatitis, potentially allowing for less steroid use

Study Summary	Study Type	Studied Population	Results
📄 A probiotic mixture helped improve eczema symptoms in children and teenagers after 12 weeks of treatment. Patients taking probiotics needed less topical steroids between weeks 6-12 of treatment compared to those taking placebo. Randomised double blind placebo controlled clinical trial to evaluate the effect of a mixture of probiotic strains on symptom severity and the use of corticosteroids in children and adolescents with atopic dermatitis. (2023)	Randomized Controlled Trial	Total Patients: 61 Severity: not available Age: 4-17 years	Patients taking probiotics had significantly better SCORAD scores compared to placebo
📄 A mixture of probiotics taken by mouth significantly improved eczema symptoms in children with moderate atopic dermatitis. Children taking probiotics needed less topical steroids to manage their condition, with an 83% improvement in symptoms compared to 24% in the placebo group. Effect of Oral Administration of a Mixture of Probiotic Strains on SCORAD Index and Use of Topical Steroids in Young Patients With Moderate Atopic Dermatitis: A Randomized Clinical Trial (2018)	Randomized Controlled Trial	Total Patients: 50 Severity: moderate Age: 4-17 years	Probiotics led to a significantly greater improvement in eczema severity compared to placebo

Probiotics appear to be safe with very few reported side effects. Most studies reported similar adverse event rates between probiotic and placebo groups

Study Summary	Study Type	Studied Population	Results
📄 The probiotic LGG helped improve eczema symptoms in young children when taken daily for 12 weeks. Children who took the probiotic needed less rescue medication and had better quality of life. The benefits were linked to positive changes in both gut and skin bacteria. Therapeutic effects elicited by the probiotic Lacticaseibacillus rhamnosus GG in children with atopic dermatitis. The results of the ProPAD trial (2022)	Randomized Controlled Trial	Total Patients: 100 Severity: not available Age: 6-36 months	Significant improvement in eczema severity that was maintained after treatment
📄 An 8-week treatment with probiotics (beneficial bacteria) and prebiotics improved eczema symptoms in children. The severity of eczema decreased significantly, with the percentage of children having moderate-severe disease dropping from 92.4% to 28.1%. Effect of synbiotic supplementation on children with atopic dermatitis: an observational prospective study (2018)	Observational Study	Total Patients: 320	Significant improvement in eczema severity

Multi-strain probiotic combinations may be more effective than single strains, and treatment duration of 8-12 weeks appears to be optimal for seeing benefits

Study Summary	Study Type	Studied Population	Results
📄 An 8-week treatment with probiotics (beneficial bacteria) and prebiotics improved eczema symptoms in children. The severity of eczema decreased significantly, with the percentage of children having moderate-severe disease dropping from 92.4% to 28.1%. Effect of synbiotic supplementation on children with atopic dermatitis: an observational prospective study (2018)	Observational Study	Total Patients: 320	Significant improvement in eczema severity
📄 Taking specific probiotics and prebiotics for 12 weeks helped improve mild eczema symptoms, including itching and skin lesions. The study suggests that these supplements might help maintain stable eczema and reduce flare-ups. Probiotics and Prebiotics Orally Assumed as Disease Modifiers for Stable Mild Atopic Dermatitis: An Italian Real-Life, Multicenter, Retrospective, Observational Study (2023)	Observational Study	Total Patients: 144 Severity: mild Age: not specified (mean age 25.1 ± 17.6 years)	All measures of eczema severity showed significant improvement after 12 weeks of probiotic treatment

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 61

Severity: not available

Age: 4-17 years

Results:

Patients taking probiotics had significantly better SCORAD scores compared to placebo

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 100

Severity: not available

Age: 6-36 months

Results:

Significant improvement in eczema severity that was maintained after treatment

Summary:

Study Type:

Observational Study

Studied Population:

Total Patients: 320

Results:

Significant improvement in eczema severity

Probiotics may help reduce the need for topical corticosteroids in treating atopic dermatitis, potentially allowing for less steroid use

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 61

Severity: not available

Age: 4-17 years

Results:

Patients taking probiotics had significantly better SCORAD scores compared to placebo

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 50

Severity: moderate

Age: 4-17 years

Results:

Probiotics led to a significantly greater improvement in eczema severity compared to placebo

Probiotics appear to be safe with very few reported side effects. Most studies reported similar adverse event rates between probiotic and placebo groups

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 100

Severity: not available

Age: 6-36 months

Results:

Significant improvement in eczema severity that was maintained after treatment

Summary:

Study Type:

Observational Study

Studied Population:

Total Patients: 320

Results:

Significant improvement in eczema severity

Multi-strain probiotic combinations may be more effective than single strains, and treatment duration of 8-12 weeks appears to be optimal for seeing benefits

Summary:

Study Type:

Observational Study

Studied Population:

Total Patients: 320

Results:

Significant improvement in eczema severity

Summary:

Study Type:

Observational Study

Studied Population:

Total Patients: 144

Severity: mild

Age: not specified (mean age 25.1 ± 17.6 years)

Results:

All measures of eczema severity showed significant improvement after 12 weeks of probiotic treatment

Shea butter

(Shea butter)

If you have mild to moderate atopic dermatitis with dry, irritated skin and are looking for a natural moisturizer

Topical daily

Low

Share Cost of Medication

Get This Treatment

KEY TAKEAWAYS

Shea butter-containing cream was well-received by most patients, with 74% of users rating it as 'very good' or 'good'

Study Summary	Study Type	Studied Population	Results
📄 A cream containing shea butter was found to be acceptable by 74% of patients with atopic dermatitis. In patients who liked the cream, it reduced itching and improved quality of life. The shea butter cream worked similarly to another cream containing ceramides. Patient acceptability, efficacy, and skin biophysiology of a cream and cleanser containing lipid complex with shea butter extract versus a ceramide product for eczema	Review	Total Patients: 34	Three quarters of patients found the products acceptable

Patients who liked the shea butter cream experienced less itching and better quality of life after using it. Their itching scores improved from 6.7 to 6.0

Study Summary	Study Type	Studied Population	Results
📄 A cream containing shea butter was found to be acceptable by 74% of patients with atopic dermatitis. In patients who liked the cream, it reduced itching and improved quality of life. The shea butter cream worked similarly to another cream containing ceramides. Patient acceptability, efficacy, and skin biophysiology of a cream and cleanser containing lipid complex with shea butter extract versus a ceramide product for eczema	Review	Total Patients: 34	Three quarters of patients found the products acceptable

The shea butter cream worked just as well as other moisturizers containing ceramides (another type of skin-protecting ingredient), suggesting it's an effective alternative

Study Summary	Study Type	Studied Population	Results
📄 A cream containing shea butter was found to be acceptable by 74% of patients with atopic dermatitis. In patients who liked the cream, it reduced itching and improved quality of life. The shea butter cream worked similarly to another cream containing ceramides. Patient acceptability, efficacy, and skin biophysiology of a cream and cleanser containing lipid complex with shea butter extract versus a ceramide product for eczema	Review	Total Patients: 34	Three quarters of patients found the products acceptable

Shea butter-containing cream was well-received by most patients, with 74% of users rating it as 'very good' or 'good'

Summary:

A cream containing shea butter was found to be acceptable by 74% of patients with atopic dermatitis. In patients who liked the cream, it reduced itching and improved quality of life. The shea butter cream worked similarly to another cream containing ceramides.

Study Type:

Review

Studied Population:

Total Patients: 34

Results:

Three quarters of patients found the products acceptable

Patients who liked the shea butter cream experienced less itching and better quality of life after using it. Their itching scores improved from 6.7 to 6.0

Summary:

Study Type:

Review

Studied Population:

Total Patients: 34

Results:

Three quarters of patients found the products acceptable

The shea butter cream worked just as well as other moisturizers containing ceramides (another type of skin-protecting ingredient), suggesting it's an effective alternative

Summary:

Study Type:

Review

Studied Population:

Total Patients: 34

Results:

Three quarters of patients found the products acceptable

Vitamin D3

(Cholecalciferol)

If your child's symptoms get worse during winter or your child has confirmed low Vitamin D levels

If your symptoms get worse during winter or you have confirmed low Vitamin D levels

Oral daily

Low

Side Effect	Affected
Allergic rash
Idiosyncratic reactions

$4 per month

Get This Treatment

KEY TAKEAWAYS

Vitamin D supplementation appears to help reduce the severity of atopic dermatitis, particularly in patients with severe cases. Studies show that taking vitamin D along with standard treatments leads to greater improvement in eczema symptoms compared to standard treatment alone.

Study Summary	Study Type	Studied Population	Results
📄 Adding vitamin D supplements (1600 IU/day) to standard treatment with hydrocortisone cream helped improve severe eczema symptoms in children more than using hydrocortisone cream alone. Patients taking vitamin D showed about 56% improvement in their eczema severity compared to 42% in those taking placebo. The impact of vitamin D supplementation as an adjuvant therapy on clinical outcomes in patients with severe atopic dermatitis: A randomized controlled trial (2020)	Randomized Controlled Trial	Total Patients: 86 Severity: severe Age: pediatric (not specified)	Vitamin D supplementation led to significantly better improvement in eczema severity compared to placebo
📄 Vitamin D supplements helped reduce the severity of eczema in children under 14. After 3 months of vitamin D supplementation, patients showed significant improvement in their eczema symptoms. Vitamin D supplementation and severity of atopic dermatitis: pre-post assessment. (2021)	Observational Study	Total Patients: 152 Severity: mild to severe Age: 0-14 years	Significant improvement in eczema severity after vitamin D supplementation
📄 People with atopic dermatitis tend to have lower vitamin D levels compared to people without the condition. Taking vitamin D supplements appears to help improve symptoms of atopic dermatitis. Vitamin D Status and Efficacy of Vitamin D Supplementation in Atopic Dermatitis: A Systematic Review and Meta-Analysis (2016)	Review		Vitamin D supplementation improved atopic dermatitis symptoms

Pregnant women taking vitamin D supplements (1000 IU daily) during pregnancy may help reduce their baby's risk of developing eczema in the first year of life, particularly if they breastfeed for more than one month.

Study Summary	Study Type	Studied Population	Results
📄 Pregnant women who took vitamin D supplements (1000 IU daily) during pregnancy had babies with a 45% lower chance of developing eczema at 12 months of age. This protective effect was stronger in babies who were breastfed for at least 1 month, but the effect became weaker as children got older. Maternal antenatal vitamin D supplementation and offspring risk of atopic eczema in the first 4 years of life: evidence from a randomized controlled trial (2022)	Randomized Controlled Trial	Total Patients: 635 Severity: not available Age: 0-48 months	Significant reduction in eczema at 12 months, effect weakens over time
📄 Pregnant mothers who took vitamin D supplements (1000 IU daily) had babies with lower risk of developing eczema at 12 months of age. This effect was stronger in mothers with normal or slightly overweight BMI, but didn't work as well in mothers with obesity. PA30 The modifying effect of maternal body mass index on the influence of maternal vitamin D supplementation on offspring risk of atopic eczema (2023)	JournalArticle	Total Patients: 636 Severity: not available Age: 0-48 months

People with atopic dermatitis tend to have lower vitamin D levels compared to those without the condition. This is especially true in children with atopic dermatitis.

Study Summary	Study Type	Studied Population	Results
📄 People with atopic dermatitis tend to have lower vitamin D levels compared to people without the condition. Taking vitamin D supplements appears to help improve symptoms of atopic dermatitis. Vitamin D Status and Efficacy of Vitamin D Supplementation in Atopic Dermatitis: A Systematic Review and Meta-Analysis (2016)	Review		Vitamin D supplementation improved atopic dermatitis symptoms
📄 Children with atopic dermatitis tend to have lower vitamin D levels compared to healthy children, especially those with severe eczema. Taking vitamin D supplements appears to help improve eczema symptoms in children. Serum Vitamin D Level and Efficacy of Vitamin D Supplementation in Children with Atopic Dermatitis: A Systematic Review and Meta-analysis (2022)	Meta-Analysis		Children with AD had significantly lower vitamin D levels than healthy children

The effectiveness of vitamin D supplementation may vary based on factors like body weight - people with higher body mass index (BMI) may need higher doses to see benefits.

Study Summary	Study Type	Studied Population	Results
📄 Pregnant mothers who took vitamin D supplements (1000 IU daily) had babies with lower risk of developing eczema at 12 months of age. This effect was stronger in mothers with normal or slightly overweight BMI, but didn't work as well in mothers with obesity. PA30 The modifying effect of maternal body mass index on the influence of maternal vitamin D supplementation on offspring risk of atopic eczema (2023)	JournalArticle	Total Patients: 636 Severity: not available Age: 0-48 months

Summary:

Adding vitamin D supplements (1600 IU/day) to standard treatment with hydrocortisone cream helped improve severe eczema symptoms in children more than using hydrocortisone cream alone. Patients taking vitamin D showed about 56% improvement in their eczema severity compared to 42% in those taking placebo.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 86

Severity: severe

Age: pediatric (not specified)

Results:

Vitamin D supplementation led to significantly better improvement in eczema severity compared to placebo

Summary:

Vitamin D supplements helped reduce the severity of eczema in children under 14. After 3 months of vitamin D supplementation, patients showed significant improvement in their eczema symptoms.

Study Type:

Observational Study

Studied Population:

Total Patients: 152

Severity: mild to severe

Age: 0-14 years

Results:

Significant improvement in eczema severity after vitamin D supplementation

Summary:

People with atopic dermatitis tend to have lower vitamin D levels compared to people without the condition. Taking vitamin D supplements appears to help improve symptoms of atopic dermatitis.

Study Type:

Review

Studied Population:

Results:

Vitamin D supplementation improved atopic dermatitis symptoms

Summary:

Pregnant women who took vitamin D supplements (1000 IU daily) during pregnancy had babies with a 45% lower chance of developing eczema at 12 months of age. This protective effect was stronger in babies who were breastfed for at least 1 month, but the effect became weaker as children got older.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 635

Severity: not available

Age: 0-48 months

Results:

Significant reduction in eczema at 12 months, effect weakens over time

Summary:

Pregnant mothers who took vitamin D supplements (1000 IU daily) had babies with lower risk of developing eczema at 12 months of age. This effect was stronger in mothers with normal or slightly overweight BMI, but didn't work as well in mothers with obesity.

Study Type:

JournalArticle

Studied Population:

Total Patients: 636

Severity: not available

Age: 0-48 months

Results:

People with atopic dermatitis tend to have lower vitamin D levels compared to those without the condition. This is especially true in children with atopic dermatitis.

Summary:

People with atopic dermatitis tend to have lower vitamin D levels compared to people without the condition. Taking vitamin D supplements appears to help improve symptoms of atopic dermatitis.

Study Type:

Review

Studied Population:

Results:

Vitamin D supplementation improved atopic dermatitis symptoms

Summary:

Children with atopic dermatitis tend to have lower vitamin D levels compared to healthy children, especially those with severe eczema. Taking vitamin D supplements appears to help improve eczema symptoms in children.

Study Type:

Meta-Analysis

Studied Population:

Results:

Children with AD had significantly lower vitamin D levels than healthy children

The effectiveness of vitamin D supplementation may vary based on factors like body weight - people with higher body mass index (BMI) may need higher doses to see benefits.

Summary:

Study Type:

JournalArticle

Studied Population:

Total Patients: 636

Severity: not available

Age: 0-48 months

Results:

Turmeric

(Curcumin)

If you are looking for a natural, anti-inflammatory remedy

Topical daily

Low

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KEY TAKEAWAYS

Turmeric can be effective for treating eczema symptoms when applied topically (on the skin) in different forms like micro emulsion, gel, and ointment. Each form works better for different symptoms - micro emulsions help reduce redness and swelling, gels help with itching, and ointments work better for scaling and thickened skin.

Study Summary	Study Type	Studied Population	Results
📄 Different formulations (micro emulsion, gel, and ointment) containing turmeric and other herbs were tested in eczema patients. The micro emulsion was best for reducing redness and swelling, the gel was best for itching, and the ointment was most effective for scaling and thickened skin. Formulation and clinical evaluation of topical dosage forms of Indian Penny Wort, walnut and turmeric in eczema	Randomized Controlled Trial	Total Patients: 360	All formulations showed significant improvement compared to placebo for various symptoms

Turmeric-based treatments performed significantly better than placebo (dummy treatments), suggesting it's a promising natural alternative for eczema treatment.

Study Summary	Study Type	Studied Population	Results
📄 Different formulations (micro emulsion, gel, and ointment) containing turmeric and other herbs were tested in eczema patients. The micro emulsion was best for reducing redness and swelling, the gel was best for itching, and the ointment was most effective for scaling and thickened skin. Formulation and clinical evaluation of topical dosage forms of Indian Penny Wort, walnut and turmeric in eczema	Randomized Controlled Trial	Total Patients: 360	All formulations showed significant improvement compared to placebo for various symptoms

Summary:

Different formulations (micro emulsion, gel, and ointment) containing turmeric and other herbs were tested in eczema patients. The micro emulsion was best for reducing redness and swelling, the gel was best for itching, and the ointment was most effective for scaling and thickened skin.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 360

Results:

All formulations showed significant improvement compared to placebo for various symptoms

Turmeric-based treatments performed significantly better than placebo (dummy treatments), suggesting it's a promising natural alternative for eczema treatment.

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 360

Results:

All formulations showed significant improvement compared to placebo for various symptoms

Honey

(Manuka honey)

If you are looking for a natural add-on treatment

Topical daily

Low

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KEY TAKEAWAYS

Honey appears to be effective in treating atopic dermatitis symptoms, with clinical studies showing significant improvement in skin severity scores after treatment

Study Summary	Study Type	Studied Population	Results
📄 A mixture of honey, beeswax, and olive oil helped improve symptoms in 8 out of 10 patients with atopic dermatitis after 2 weeks. The mixture also allowed some patients to reduce their steroid medication use by 75% without their condition getting worse. Topical application of natural honey, beeswax and olive oil mixture for atopic dermatitis or psoriasis: partially controlled, single-blinded study	Clinical Trial	Total Patients: 21 Severity: not available Age: not available	80% of patients improved with honey mixture

Honey works through multiple mechanisms including reducing inflammation, inhibiting certain bacterial toxins, and preventing mast cells from releasing histamine (which causes itching)

Study Summary	Study Type	Studied Population	Results

When combined with conventional corticosteroid treatments, honey mixtures allowed patients to reduce their steroid dose by 75% while maintaining improvement

Study Summary	Study Type	Studied Population	Results
📄 A mixture of honey, beeswax, and olive oil helped improve symptoms in 8 out of 10 patients with atopic dermatitis after 2 weeks. The mixture also allowed some patients to reduce their steroid medication use by 75% without their condition getting worse. Topical application of natural honey, beeswax and olive oil mixture for atopic dermatitis or psoriasis: partially controlled, single-blinded study	Clinical Trial	Total Patients: 21 Severity: not available Age: not available	80% of patients improved with honey mixture

Honey appears to be safe for topical use, with studies showing it can actually increase skin cell growth at certain concentrations

Study Summary	Study Type	Studied Population	Results

Honey appears to be effective in treating atopic dermatitis symptoms, with clinical studies showing significant improvement in skin severity scores after treatment

Summary:

A mixture of honey, beeswax, and olive oil helped improve symptoms in 8 out of 10 patients with atopic dermatitis after 2 weeks. The mixture also allowed some patients to reduce their steroid medication use by 75% without their condition getting worse.

Study Type:

Clinical Trial

Studied Population:

Total Patients: 21

Severity: not available

Age: not available

Results:

80% of patients improved with honey mixture

Honey works through multiple mechanisms including reducing inflammation, inhibiting certain bacterial toxins, and preventing mast cells from releasing histamine (which causes itching)

When combined with conventional corticosteroid treatments, honey mixtures allowed patients to reduce their steroid dose by 75% while maintaining improvement

Summary:

Study Type:

Clinical Trial

Studied Population:

Total Patients: 21

Severity: not available

Age: not available

Results:

80% of patients improved with honey mixture

Honey appears to be safe for topical use, with studies showing it can actually increase skin cell growth at certain concentrations

Zinc

(Zinc)

If your baby is experiencing a rash

To treat minor skin irritations

Topical daily

Low

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KEY TAKEAWAYS

Zinc levels are often lower in people with atopic dermatitis, and oral zinc supplements may help improve symptoms in patients who have low zinc levels. Improvements were seen in skin condition, itching, and sleep.

Study Summary	Study Type	Studied Population	Results
📄 Children with atopic dermatitis had lower zinc levels in their hair compared to healthy children. When children with low zinc levels were given zinc supplements, their eczema symptoms, skin barrier function, and itching improved more than those who didn't receive supplements. Hair zinc levels and the efficacy of oral zinc supplementation in patients with atopic dermatitis	Randomized Controlled Trial	Total Patients: 58	Zinc supplementation successfully increased hair zinc levels

A cream containing zinc oxide along with other ingredients (starch, glycyrretinic acid, and bisabolol) was effective in treating mild-to-moderate atopic dermatitis in children, reducing symptoms by 74% after 6 weeks of use. This cream is steroid-free and was well-tolerated.

Study Summary	Study Type	Studied Population	Results

Not all studies show benefits of oral zinc supplements. One study found no improvement in eczema symptoms when children took zinc sulphate supplements for 8 weeks.

Study Summary	Study Type	Studied Population	Results

When combined with a steroid cream (Clobetasol), adding zinc sulphate improved the treatment's effectiveness for hand eczema and reduced the chance of the condition returning after treatment.

Study Summary	Study Type	Studied Population	Results
📄 A combination cream containing Clobetasol and zinc sulphate was more effective in treating chronic hand eczema compared to Clobetasol alone. The combination treatment also showed lower recurrence rates of eczema after treatment. The efficacy of '0.05% Clobetasol + 2.5% zinc sulphate' cream vs. '0.05% Clobetasol alone' cream in the treatment of the chronic hand eczema: a double-blind study	Randomized Controlled Trial	Total Patients: 47	Combination cream showed significantly better improvement in all measured symptoms and lower recurrence rates compared to Clobetasol alone

Summary:

Children with atopic dermatitis had lower zinc levels in their hair compared to healthy children. When children with low zinc levels were given zinc supplements, their eczema symptoms, skin barrier function, and itching improved more than those who didn't receive supplements.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 58

Results:

Zinc supplementation successfully increased hair zinc levels

Not all studies show benefits of oral zinc supplements. One study found no improvement in eczema symptoms when children took zinc sulphate supplements for 8 weeks.

When combined with a steroid cream (Clobetasol), adding zinc sulphate improved the treatment's effectiveness for hand eczema and reduced the chance of the condition returning after treatment.

Summary:

A combination cream containing Clobetasol and zinc sulphate was more effective in treating chronic hand eczema compared to Clobetasol alone. The combination treatment also showed lower recurrence rates of eczema after treatment.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 47

Results:

Combination cream showed significantly better improvement in all measured symptoms and lower recurrence rates compared to Clobetasol alone

Omega-6

(Gamma-linolenic acid (GLA))

As a supplement to medicinal treatments

Oral daily

Low

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Discuss with a Dermatologist

KEY TAKEAWAYS

The effectiveness of gamma-linolenic acid (GLA) for treating eczema shows mixed results. Some studies found it helped reduce symptoms like itching, redness, and oozing, while others found no significant improvement.

Study Summary	Study Type	Studied Population	Results
📄 Gamma-linolenic acid treatment showed some improvement in itch symptoms and reduced the need for antihistamines in infants with atopic dermatitis. While none of the children showed complete recovery, the treatment was found to be safe with no side effects. The efficacy and safety of gamma-linolenic acid in the treatment of infantile atopic dermatitis	Clinical Trial	Severity: not available Age: infants (mean age 11.4 months)	Partial improvement in skin symptoms but no complete recovery

GLA appears to be safe for both adults and children, with no significant side effects reported in multiple studies.

Study Summary	Study Type	Studied Population	Results
📄 Gamma-linolenic acid treatment showed some improvement in itch symptoms and reduced the need for antihistamines in infants with atopic dermatitis. While none of the children showed complete recovery, the treatment was found to be safe with no side effects. The efficacy and safety of gamma-linolenic acid in the treatment of infantile atopic dermatitis	Clinical Trial	Severity: not available Age: infants (mean age 11.4 months)	Partial improvement in skin symptoms but no complete recovery

When used preventively in infants at high risk for eczema, GLA supplementation didn't prevent eczema from developing, but it might help reduce the severity of symptoms when they do occur.

Study Summary	Study Type	Studied Population	Results
📄 Early supplementation with gamma-linolenic acid (GLA) in high-risk infants showed a trend toward reducing the severity of atopic dermatitis, though it didn't prevent the development of allergies. Infants receiving GLA had slightly less severe eczema symptoms compared to those receiving placebo. Gamma-linolenic acid supplementation for prophylaxis of atopic dermatitis--a randomized controlled trial in infants at high familial risk	Clinical Trial	Total Patients: 118 Severity: not available Age: 0-12 months	Trend toward lower disease severity with GLA supplementation (p=0.09)
📄 Supplementing infants' diet with gamma-linolenic acid (GLA) did not prevent atopic dermatitis. However, in infants who did develop atopic dermatitis, GLA supplementation appeared to reduce levels of IgE (an antibody associated with allergic responses) during their first year. Impact of early dietary gamma-linolenic acid supplementation on atopic eczema in infancy	Randomized Controlled Trial	Total Patients: 131 Severity: not available Age: infants (newborn to 1 year)	GLA supplementation did not prevent AD development

Summary:

Gamma-linolenic acid treatment showed some improvement in itch symptoms and reduced the need for antihistamines in infants with atopic dermatitis. While none of the children showed complete recovery, the treatment was found to be safe with no side effects.

Study Type:

Clinical Trial

Studied Population:

Severity: not available

Age: infants (mean age 11.4 months)

Results:

Partial improvement in skin symptoms but no complete recovery

GLA appears to be safe for both adults and children, with no significant side effects reported in multiple studies.

Summary:

Study Type:

Clinical Trial

Studied Population:

Severity: not available

Age: infants (mean age 11.4 months)

Results:

Partial improvement in skin symptoms but no complete recovery

When used preventively in infants at high risk for eczema, GLA supplementation didn't prevent eczema from developing, but it might help reduce the severity of symptoms when they do occur.

Summary:

Early supplementation with gamma-linolenic acid (GLA) in high-risk infants showed a trend toward reducing the severity of atopic dermatitis, though it didn't prevent the development of allergies. Infants receiving GLA had slightly less severe eczema symptoms compared to those receiving placebo.

Study Type:

Clinical Trial

Studied Population:

Total Patients: 118

Severity: not available

Age: 0-12 months

Results:

Trend toward lower disease severity with GLA supplementation (p=0.09)

Summary:

Supplementing infants' diet with gamma-linolenic acid (GLA) did not prevent atopic dermatitis. However, in infants who did develop atopic dermatitis, GLA supplementation appeared to reduce levels of IgE (an antibody associated with allergic responses) during their first year.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 131

Severity: not available

Age: infants (newborn to 1 year)

Results:

GLA supplementation did not prevent AD development

Omega-3

(Polyunsaturated fatty acid)

As a supplement to other treatments

As a supplement to other treatments, especially during pregnancy and breastfeeding

Oral daily

Low

Side Effect	Affected
Eructation	4%
Dyspepsia	3%
Taste perversion	4%
Constipation

$7.50 per month

($4.50 - $10)

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KEY TAKEAWAYS

The effectiveness of fish oil supplements for eczema may depend on genetics. In pregnant women with a specific genetic type (TT genotype), taking fish oil during pregnancy reduced their children's risk of developing eczema. However, for women with different genetic types, it either had no effect or could increase the risk.

Study Summary	Study Type	Studied Population	Results
📄 This study looked at whether taking fish oil supplements during pregnancy could prevent eczema in children. The effectiveness depended on the mother's genes - it helped prevent eczema in children whose mothers had a specific genetic type (TT genotype) but increased the risk in mothers with a different genetic type (CC genotype). Prenatal Fish Oil Supplementation, Maternal COX1 Genotype, and Childhood Atopic Dermatitis: A Secondary Analysis of a Randomized Clinical Trial. (2024)	Randomized Controlled Trial	Total Patients: 635 Severity: not available Age: 0-10 years	No overall effect on AD risk when not considering genetic differences

When combined with gamma-linolenic acid (GLA) and vitamin D, fish oil supplements showed promising results in children with eczema, reducing symptom severity, itching, and the need for steroid creams. It also improved sleep quality and overall quality of life.

Study Summary	Study Type	Studied Population	Results
📄 Children with eczema who took omega-3 supplements combined with GLA from blackcurrant seed oil showed significant improvement in their symptoms after 4 months. The treatment reduced skin inflammation, itching, and the need for steroid creams by about half. Effect of Omega-3 Polyunsaturated Fatty Acid Supplementation on Clinical Outcome of Atopic Dermatitis in Children (2024)	Randomized Controlled Trial	Total Patients: 52 Severity: moderate to severe Age: children

Taking fish oil supplements during pregnancy and early breastfeeding (up to 6 months after birth) did not show clear benefits in preventing allergic conditions, including eczema, in children up to age 2.

Study Summary	Study Type	Studied Population	Results
📄 Taking fish oil and/or probiotics during pregnancy and up to 6 months after giving birth did not reduce the risk of atopic eczema or food allergies in children up to 2 years of age. Probiotics alone did reduce the risk of recurring wheezing in 2-year-olds. Maternal fish oil and/or probiotics intervention: Allergic diseases in children up to two years old (2023)	Randomized Controlled Trial	Total Patients: 439 Severity: not available Age: 0-2 years	No benefit of fish oil and/or probiotics in preventing atopic eczema

Summary:

This study looked at whether taking fish oil supplements during pregnancy could prevent eczema in children. The effectiveness depended on the mother's genes - it helped prevent eczema in children whose mothers had a specific genetic type (TT genotype) but increased the risk in mothers with a different genetic type (CC genotype).

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 635

Severity: not available

Age: 0-10 years

Results:

No overall effect on AD risk when not considering genetic differences

Summary:

Children with eczema who took omega-3 supplements combined with GLA from blackcurrant seed oil showed significant improvement in their symptoms after 4 months. The treatment reduced skin inflammation, itching, and the need for steroid creams by about half.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 52

Severity: moderate to severe

Age: children

Results:

Summary:

Taking fish oil and/or probiotics during pregnancy and up to 6 months after giving birth did not reduce the risk of atopic eczema or food allergies in children up to 2 years of age. Probiotics alone did reduce the risk of recurring wheezing in 2-year-olds.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 439

Severity: not available

Age: 0-2 years

Results:

No benefit of fish oil and/or probiotics in preventing atopic eczema

Olive oil

(Olive oil)

If you are looking for a gentle and natural moisturizer

Topical daily

Low

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KEY TAKEAWAYS

Olive oil, when combined with honey and beeswax in equal parts, can help improve symptoms of atopic dermatitis. In one study, 80% of patients showed significant improvement after 2 weeks of use.

Study Summary	Study Type	Studied Population	Results
📄 A mixture of honey, olive oil, and beeswax helped improve symptoms in 8 out of 10 patients with atopic dermatitis after 2 weeks. The mixture also allowed some patients to reduce their steroid medication use by 75% without their condition getting worse. Topical application of natural honey, beeswax and olive oil mixture for atopic dermatitis or psoriasis: partially controlled, single-blinded study	Clinical Trial	Total Patients: 21 Severity: not available Age: not available	The honey-olive oil-beeswax mixture showed effectiveness in treating atopic dermatitis

Virgin olive oil can help moisturize dry skin in atopic dermatitis patients, though it may not be as effective as some other natural oils like coconut oil.

Study Summary	Study Type	Studied Population	Results
📄 Virgin olive oil helped moisturize dry skin and reduce severity in adults with atopic dermatitis. However, it was less effective than coconut oil at removing bacteria (Staphylococcus aureus) from the skin, with 50% of olive oil users still having bacteria after treatment compared to 5% in the coconut oil group. Novel antibacterial and emollient effects of coconut and virgin olive oils in adult atopic dermatitis	Randomized Controlled Trial	Total Patients: 52 Severity: not available Age: 18+	Both oils reduced disease severity, but coconut oil showed greater improvement

When used alongside prescription steroid medications, a mixture containing olive oil allowed patients to reduce their steroid use by 75% while maintaining skin improvement.

Study Summary	Study Type	Studied Population	Results
📄 A mixture of honey, olive oil, and beeswax helped improve symptoms in 8 out of 10 patients with atopic dermatitis after 2 weeks. The mixture also allowed some patients to reduce their steroid medication use by 75% without their condition getting worse. Topical application of natural honey, beeswax and olive oil mixture for atopic dermatitis or psoriasis: partially controlled, single-blinded study	Clinical Trial	Total Patients: 21 Severity: not available Age: not available	The honey-olive oil-beeswax mixture showed effectiveness in treating atopic dermatitis

While olive oil has some antibacterial properties against Staphylococcus aureus (a bacteria commonly found on eczema skin), studies suggest it may be less effective than alternatives like coconut oil for this purpose.

Study Summary	Study Type	Studied Population	Results
📄 Virgin olive oil helped moisturize dry skin and reduce severity in adults with atopic dermatitis. However, it was less effective than coconut oil at removing bacteria (Staphylococcus aureus) from the skin, with 50% of olive oil users still having bacteria after treatment compared to 5% in the coconut oil group. Novel antibacterial and emollient effects of coconut and virgin olive oils in adult atopic dermatitis	Randomized Controlled Trial	Total Patients: 52 Severity: not available Age: 18+	Both oils reduced disease severity, but coconut oil showed greater improvement

Olive oil, when combined with honey and beeswax in equal parts, can help improve symptoms of atopic dermatitis. In one study, 80% of patients showed significant improvement after 2 weeks of use.

Summary:

A mixture of honey, olive oil, and beeswax helped improve symptoms in 8 out of 10 patients with atopic dermatitis after 2 weeks. The mixture also allowed some patients to reduce their steroid medication use by 75% without their condition getting worse.

Study Type:

Clinical Trial

Studied Population:

Total Patients: 21

Severity: not available

Age: not available

Results:

The honey-olive oil-beeswax mixture showed effectiveness in treating atopic dermatitis

Virgin olive oil can help moisturize dry skin in atopic dermatitis patients, though it may not be as effective as some other natural oils like coconut oil.

Summary:

Virgin olive oil helped moisturize dry skin and reduce severity in adults with atopic dermatitis. However, it was less effective than coconut oil at removing bacteria (Staphylococcus aureus) from the skin, with 50% of olive oil users still having bacteria after treatment compared to 5% in the coconut oil group.

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 52

Severity: not available

Age: 18+

Results:

Both oils reduced disease severity, but coconut oil showed greater improvement

When used alongside prescription steroid medications, a mixture containing olive oil allowed patients to reduce their steroid use by 75% while maintaining skin improvement.

Summary:

Study Type:

Clinical Trial

Studied Population:

Total Patients: 21

Severity: not available

Age: not available

Results:

The honey-olive oil-beeswax mixture showed effectiveness in treating atopic dermatitis

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 52

Severity: not available

Age: 18+

Results:

Both oils reduced disease severity, but coconut oil showed greater improvement

HIGHEST EFFICACY IN CATEGORY

Vitamin B12 (Cobalamin)

Who is this for?:

As an add-on alongside other therapies

Effectiveness:

Side Effects:

Low

Cost:

Delivery:

Oral daily

See Evidence

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KEY TAKEAWAYS

Study Summary	Study Type	Studied Population	Results
📄 A vitamin B12 cream was compared to a standard moisturizing cream for treating mild eczema. The vitamin B12 cream reduced eczema severity by 77.6% compared to 33.5% with the standard cream after 12 weeks of use. Superiority of a vitamin B12‐barrier cream compared with standard glycerol‐petrolatum‐based emollient cream in the treatment of atopic dermatitis: A randomized, left‐to‐right comparative trial (2017)	Randomized Controlled Trial	Total Patients: 22 Severity: mild Age: not available	Vitamin B12 cream was more than twice as effective as standard moisturizer in reducing eczema severity

Study Summary	Study Type	Studied Population	Results
📄 In a case study of one patient with severe eczema, researchers found that low vitamin B12 levels were associated with worse eczema symptoms. When the patient took vitamin B12 supplements, their eczema improved significantly. Vitamin B12 and Atopic Dermatitis: Any Therapeutic Relevance For Oral Supplementation? (2020)	Case Reports	Total Patients: 1 Severity: severe Age: 18	Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Vitamin B12 has anti-inflammatory properties and can help regulate the immune system, which may explain why it helps with eczema symptoms

Study Summary	Study Type	Studied Population	Results
📄 In a case study of one patient with severe eczema, researchers found that low vitamin B12 levels were associated with worse eczema symptoms. When the patient took vitamin B12 supplements, their eczema improved significantly. Vitamin B12 and Atopic Dermatitis: Any Therapeutic Relevance For Oral Supplementation? (2020)	Case Reports	Total Patients: 1 Severity: severe Age: 18	Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 22

Severity: mild

Age: not available

Results:

Vitamin B12 cream was more than twice as effective as standard moisturizer in reducing eczema severity

Summary:

Study Type:

Case Reports

Studied Population:

Total Patients: 1

Severity: severe

Age: 18

Results:

Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Vitamin B12 has anti-inflammatory properties and can help regulate the immune system, which may explain why it helps with eczema symptoms

Summary:

Study Type:

Case Reports

Studied Population:

Total Patients: 1

Severity: severe

Age: 18

Results:

Patient showed meaningful improvement in eczema severity score when taking vitamin B12 supplements

Coconut Oil (Virgin Coconut Oil)

Who is this for?:

If you are looking for a gentle and natural moisturizer that may help reduce inflammation and bacterial colonization

If you are looking for a gentle and natural moisturizer for your child that may help reduce inflammation and bacterial colonization

Effectiveness:

Side Effects:

Low

Cost:

Delivery:

Topical as needed daily

See Evidence

Get This Treatment

KEY TAKEAWAYS

Study Summary	Study Type	Studied Population	Results
📄 A cream containing coconut and sunflower seed oil derivatives improved itch by 65.6% compared to 43.8% with the control cream in people with mild-to-moderate eczema. The treatment also reduced the need for steroid creams and decreased harmful bacteria on the skin. Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis. (2024)	Randomized Controlled Trial	Total Patients: 32 Severity: mild to moderate Age: 18+	Significantly better itch relief in treatment group (p=0.013)

When used in a specialized formulation, coconut oil derivatives can help reduce the need for topical steroids in eczema treatment, particularly in the early weeks of treatment

Study Summary	Study Type	Studied Population	Results
📄 A cream containing coconut and sunflower seed oil derivatives improved itch by 65.6% compared to 43.8% with the control cream in people with mild-to-moderate eczema. The treatment also reduced the need for steroid creams and decreased harmful bacteria on the skin. Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis. (2024)	Randomized Controlled Trial	Total Patients: 32 Severity: mild to moderate Age: 18+	Significantly better itch relief in treatment group (p=0.013)

Coconut oil-based treatments may help reduce harmful bacteria (Staphylococcus aureus) on the skin of eczema patients

Study Summary	Study Type	Studied Population	Results
📄 A cream containing coconut and sunflower seed oil derivatives improved itch by 65.6% compared to 43.8% with the control cream in people with mild-to-moderate eczema. The treatment also reduced the need for steroid creams and decreased harmful bacteria on the skin. Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis. (2024)	Randomized Controlled Trial	Total Patients: 32 Severity: mild to moderate Age: 18+	Significantly better itch relief in treatment group (p=0.013)

Coconut oil is one of the most commonly used traditional home remedies for eczema treatment, particularly in Indian households

Study Summary	Study Type	Studied Population	Results
📄 In a study of 150 children in India, coconut oil was the most commonly used home remedy for treating eczema/atopic dermatitis, followed by olive oil and mustard oil. The study looked at various home remedies parents used before visiting a doctor. Home remedies in different pediatric dermatoses: An observational study (2020)	Observational Study	Total Patients: 150

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 32

Severity: mild to moderate

Age: 18+

Results:

Significantly better itch relief in treatment group (p=0.013)

When used in a specialized formulation, coconut oil derivatives can help reduce the need for topical steroids in eczema treatment, particularly in the early weeks of treatment

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 32

Severity: mild to moderate

Age: 18+

Results:

Significantly better itch relief in treatment group (p=0.013)

Coconut oil-based treatments may help reduce harmful bacteria (Staphylococcus aureus) on the skin of eczema patients

Summary:

Study Type:

Randomized Controlled Trial

Studied Population:

Total Patients: 32

Severity: mild to moderate

Age: 18+

Results:

Significantly better itch relief in treatment group (p=0.013)

Coconut oil is one of the most commonly used traditional home remedies for eczema treatment, particularly in Indian households

Summary:

Study Type:

Observational Study

Studied Population:

Total Patients: 150

Results:

Probiotics (Lactobacillus, Bifidobacterium)

Who is this for?:

As a complementary treatment alongside standard therapies

As a complementary treatment for children with moderate atopic dermatitis

Effectiveness:

Side Effects:

Low

Cost: