lemma health
Dupixent (dupilumab)
Available Online
Injection
Every 2 weeks
Copay Card Available
Available by Prescription
As Low as $0
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  • 65-75% of patients achieve clear or almost clear skin
  • 90% of patients see at least 75% improvement
  • Maintains effectiveness for up to 5 years
  • 75% of patients experience significant itch reduction
  • Mild to moderate reactions (nose/throat inflammation, pink eye, injection site reactions)
“I'm just posting this to share my experience hoping it gets to someone on this sub who's going through what I was going through. I joined this sub on another …”
- Patient review
“I'm 16 today, and my flare started when I was 13. 1 year ago, this was my skin. (NSFW, very very bad skin - https://www.reddit.com/r/eczema/s/GMd4YAn20A). At this point, I was …”
- Patient review
“I started Dupixent about 5 weeks ago and had no hope at all because I’ve been on it before and it did not do a thing then lol. But! My …”
- Patient review
How well does Dupixent work?
Dupixent is above average for atopic dermatitis "Biologics" treatments.
What is the evidence behind Dupixent?
Dupilumab significantly improves signs and symptoms of moderate-to-severe atopic dermatitis, including skin lesions, itching, and quality of life compared to placebo. In clinical trials, 60-70% of patients achieved a 75% improvement in disease severity scores after 16 weeks of treatment.
What does the research say?
Study Summary

Dupilumab is an effective treatment for moderate-to-severe atopic dermatitis in adults and children as young as 6 months. Clinical trials show that 60-70% of patients achieve significant improvement in their eczema symptoms, including reduction in itch and skin clearance.

Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis.
Study Type
Comment
Studied Population
Severity: moderate to severe
Age: 6 months and older
Results
Dupilumab significantly improved eczema symptoms compared to placebo
Study Summary

Dupilumab significantly improved quality of life in adults with moderate-to-severe eczema. The improvements were meaningful in daily life, particularly reducing pain/discomfort, anxiety/depression, and helping with usual activities.

Dupilumab Improves General Health-Related Quality-of-Life in Patients with Moderate-to-Severe Atopic Dermatitis: Pooled Results from Two Randomized, Controlled Phase 3 Clinical Trials
Study Type
Studied Population
Total Patients: 1,379
Severity: moderate to severe
Age: 18+
Results
Both weekly and every 2 weeks dupilumab treatment led to significantly greater improvements in quality of life compared to placebo
Study Summary

Dupilumab combined with topical steroids was significantly more effective than steroids alone in treating moderate-to-severe eczema. After 16 weeks, about 39% of patients on dupilumab had clear or almost clear skin compared to 12% on placebo, and these improvements lasted for the full year of treatment.

Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial
Study Type
Clinical Trial
Studied Population
Total Patients: 740
Severity: moderate to severe
Age: 18+
Results
What are other patients saying?
  • How life feels after being eczema free, from a long time poster on this sub.
    July 26, 2024
    This will possibly be my last post on this sub, because I like to think of my eczema as "cured" (I know I'll technically have it until I die.) My eczema got severe on October 2023, had it only on my neck and face before that. I was a little depressed, was getting 3h of sleep. My most disgusting memory of it is touching my infected eyebrow and the hairs just stayed in my hand. I felt like no one relates to me, exept for people on this sub. Fast forward to june, I got my loading dose of Dupixent. My skin went from sandpaper to SOFT in just 4 days. Even though I got accepted to a school with a 7% acceptance rate, Dupixent probably is the best thing that happened to me in the last few months. And this is how life feels now; I no longer think about my skin. I can actually wear most of the things that I want and even wear minimal amount of makeup! I suddenly got approached by 2 guys at the club and one random guy in public yesterday. I no longer feel disgusting and painful when someone touches me. My eyebrows look nice again. I can use hair products and laundry softener again. I love to smell good. My purpose of writing this is to give everyone here motivation to keep going. I was in the exactly same place as you guys. And going to so many doctors actually paid off. I know it's hard, but medicine progresses and maybe in a few years, there will be even better than dupixent. Love yall! Edit: posted my before and after pics on r/eczemabs
  • Patch testing saved my life
    Jan. 16, 2024
    Lurker for a while. Had the worst flare up since January 2023 until finally in July 2023, got a patch allergy testing done and it literally saved my life. I was flaring my entire body and all the doctors forced dupixent on me but I refused because my eczema comes and goes but this past year I was at wits end. Worst it’s ever been. It turned out that I was highly allergic to propylene glycol and neospirin as well as cocamidopropyl betaine. My dermatologist was useless and told me a patch test on my back would not work since it was all flared. My sweet allergist personally put the patches on, cutting the chemicals into jigsaw puzzles and found every bit of “non red” skin. All the products my dermalogist prescribed and recommended all had PG! No wonder I was flaring. The creams and steroids all had PG! My detergent, toothpaste, shampoo all had my allergens. Took two months for my body to heal. I now have real skin. I don’t use any creams to treat eczema anymore, just moisturizer. If I have do have flare ups - Desonide ointment and tacromilus for face and neck . My products I use. I hope this will help some of you. Laundry - seventh generation free and clear Hand soap and face - vanicream facial cleanser Body soap - Cerave hydrating bar Moisturizer - Cerave moisturizing cream Toothpaste - Tom of maines fluoride Shampoo- desert essence tea tree (minimal sebderm. Used to have it on neck, ears, forehead line)
  • What I’ve learned the last 2 years
    Nov. 18, 2024
    To preface this, I’m not a doctor or professional..please always do your own research and do what works for you The last 2 years I’ve dealt with some extreme skin issues and I’ve learned a lot. Here are some of my tips: •Start with prick/patch testing and find out your allergens. If you can’t afford this or don’t have access to it, try to log the products you use in a journal each day and see if it corresponds to any flares. • Food intolerances can also cause flares. Keep a food log for a week to see if you notice anything corresponding to flares/itching • Cut. Your. Nails. File them regularly. If they’re dull you’re less likely to get cuts and cause infections • Bleach baths (controversial but I found them helpful) I’d do 10 minutes in a bath filled with warm water and 1/4 cup of bleach. Rinse with cool water after and moisturize. I’ve heard some having success with apple cider vinegar as well. I can’t vouch for it. • Zinc cream is amazing for sore/inflamed skin. I have bought tubs off of amazon or used the children’s butt paste brand. • Minera Dead Sea Salt baths (bought on Amazon) are amazing for relief and gentle exfoliation. It was the only comfort I found during my worst flares. Be sure to rinse and moisturize after. • Hypochlorus acid spray for open wounds/scratches to prevent infections (Amazon) • If you suspect your rashes to be fungal you can try a cheap anti fungal cream from the store or using a dandruff shampoo as a body wash • Skinsafeproducts is a website to help search for specific allergens in products • Stress can be a HUGE trigger. If you’re scratching from being stressed, try diverting your energy to something else that occupies your hands or brain such as video games, a craft, going on a walk, etc. • If you pick scabs frequently and find it to be disruptive to your thoughts, try to look into a picky pad. It sounds silly but it’s a sillicone mold with beads inside to pick out when you get that urge. • Find a dermatologist you trust. If you’re in the US, zocdoc is a great resource for finding doctors who take your insurance and you can read reviews on them as well. • Cotton clothing is your friend. • If you suspect you have an infection, see your doctor ASAP. • TSW is real but social media has created a lot of fear mongering around steroids. Steroids are a very helpful tool, but not a long term solution. Finding the root of the problem or another way to deal with the eczema is always preferred to long term steroid use. If you’re struggling with severe eczema, ask your doctor about dupixent. It is a biweekly injection and has helped so many with their eczema. • Lastly, be kind to yourself. EVERYONE struggles with something in life. Unfortunately with eczema we wear a lot of our struggles on the outside where they can be visible to others. Your skin condition does not define you. Therapy is a great tool alongside speaking to close family and friends about your struggles. You’ve got this! Hopefully these tips help at least one person! Sending love to you all
The medication has an acceptable safety profile, with the most common side effects being injection site reactions and conjunctivitis (eye inflammation). Serious side effects are rare. Dupilumab actually reduces skin infections compared to placebo.
What does the research say?
Study Summary

This real-world study compared the safety of dupilumab to conventional systemic treatments for atopic dermatitis over 5 years. Dupilumab showed fewer side effects related to circulatory, respiratory, and musculoskeletal systems, and infections compared to other treatments. However, it did have a higher risk of eye inflammation (conjunctivitis) compared to some other medications.

Comparison of safety profile in patients with atopic dermatitis treated with dupilumab or conventional systemic treatment: real world data from the US network.
Study Type
Comparative Study
Studied Population
Results
Study Summary

This study compared two medications for moderate-to-severe atopic dermatitis: oral upadacitinib and injectable dupilumab. Upadacitinib worked better and faster than dupilumab, with 72.4% of patients seeing major skin improvement after 16 weeks compared to 62.6% with dupilumab. However, upadacitinib had more side effects including acne and infections.

Efficacy and Safety of Upadacitinib vs Dupilumab in Adults With Moderate-to-Severe Atopic Dermatitis
Study Type
Clinical Trial
Studied Population
Total Patients: 673
Results
What are other patients saying?
  • I’m so freaking. happy.
    Oct. 2, 2024
    I have struggled with painful neck and arm eczema for the longest time ever. Showers were hell and i could barely move my neck. My arms were completely covered in this bullshit eczema. I have been researching dupixent and peoples success stories for so long and I finally had my first derm appointment today with a new doctor (woke up w a flare too). I fully expected this doc to refuse the dupixent and just put me on another steroid cream again. Doc comes in and greets me, takes one look at my eczema, and goes “would you like to try dupixent?”. Got two shots of it today already and I’m beyond happy. I’ve been suffering for so long guys I could cry.
  • I am so tired of not being able to enjoy life in my 20s
    April 9, 2024
    Short summary Had severe full body eczema for 5 years now, it does not flare, it never eases or goes away, it is constant pain and itching. It started during the pandemic and it was like a switch with my immune system turning to overdrive. Things I have tried: - steroid creams (all strengths) - light therapy - allergy testing - started therapy to manage stress - every moisturiser on the market - natural moisturisers - antifungal creams - ciclosporin - tons of hoovering - a year of prednisolone - no fragrances - many antibiotics - 5 a day - changed all my clothes to cotton - dupixent - a shower filter head - sensitive 0% shampoo - changing towels and bedsheets frequently - no moisture therapy - a very expensive professional dehumidifier - an air purifier - diets & probiotics & food diaries & vitamins - sensitive laundry detergent (ecover 0%) - I bought a brand new washing machine - I even moved house I really do feel like I've done everything and I'm so worn out. Every little thing is getting to me - I saw a couple on tiktok enjoying a cosy date together in a jacuzzi and knew I'd never be able to do that and I'm just so fed up. I'm tired of being limited by my skin and every movement being painful, it feels like I'm getting tattooed across my entire body daily. Slowly putting on weight because I can't work out or do the sports I love because sweat feels like acid. Of constantly running mental gymnastics everytime it starts to itch more than usual as to what it could be this time. Reading online 'it's your diet', 'it's your gut', 'it's the liver', 'it's this', 'it's that'. This is my 'prime' and it feels wasted. I'm laid on my bed post shower in agony with the fan blowing on my skin and i just needed to vent in a place maybe somebody can relate.
  • THERE IS NO CURE FOR ECZEMA
    Jan. 25, 2024
    holy shit yall act like google isn't a thing stop talking about fucking " has anyone cured their eczema? " there is no cure as unfortunate as it is edit: some of you are not the brightest lmao. for clarification i have been on dupixent for 4 years and havent worried about my eczema much since. yes everyone's eczema is different and there are different ways to manage and control it but that's still not a cure. this post was targeted at people on here trying to bs people by saying there's an end all be all cure.
Dupilumab works by blocking two key inflammatory proteins (IL-4 and IL-13) that drive atopic dermatitis. It is administered by subcutaneous injection every 2 weeks, with a higher initial loading dose.
What does the research say?
Study Summary

Dupilumab is the first approved targeted biological therapy for atopic dermatitis in adults and children over 6 years with moderate-to-severe disease. It works by blocking specific inflammatory proteins (IL-4 and IL-13) and helps improve skin barrier function.

Dupilumab for Atopic Dermatitis-From Clinical Trials to Molecular and Cellular Mechanisms.
Study Type
Studied Population
Severity: moderate to severe
Age: 6 years and older
Results
Study Summary

Dupilumab significantly improved eczema symptoms and skin healing over 16 weeks of treatment. The medication worked by reducing inflammation in the skin and helping restore normal skin barrier function.

Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis
Study Type
Clinical Trial
Studied Population
Total Patients: 54
Severity: moderate-to-severe
Age: not available
Results
Dupilumab improved skin healing at both molecular and cellular levels
What are other patients saying?
  • Dupixent has changed my life.
    May 8, 2024
    I'm 16 today, and my flare started when I was 13. 1 year ago, this was my skin. (NSFW, very very bad skin - https://www.reddit.com/r/eczema/s/GMd4YAn20A). At this point, I was 2 years into my flare. It had started in 2020, and it just got progressively worse. I had just finished phototherapy, and failed Methotrexate (live function rose), and I was waiting for a referral to get Dupixent at a local children/teens hospital. Then, I started Dupixent. Today, my skin is clear. I don't use steroids anymore and if I do, it's for a week or two before stopping again., I don't really even use Protopic anymore. Sure, I still am still really itchy, and I do live in a constant fear of a flare - but, at the same time, I've got my life back. Sure, there are side effects. My vision has gotten a bit worse, and my eyes are getting fucked - but it's manageable. Dupixent is the most amazing drug to ever grace this earth. It's changed my life forever. That may sound trivial, but it is true. Of course, I still have really bad patches where stress flares me up, but for the most part, I am consistently in the mild eczema category, ever since starting dupixent. Last year, I was very anxious, scared and pessimistic of all these medicines, treatments and how they "probably wouldn't work". But now, I can go outside and wear shorts, I've started rolling up my sleeves, I don't really care if people see my skin, because it doesn't look bad anymore. It's the small trivial things that really make me look back and go - oh shit. Being a teenager, I have lost out on a lot of my years of "fun". I didn't get to participate in sports because of how debilitating my skin has been. I didn't get to go on holidays to the beach because of how water was like acid. I got mocked, bullied, teased relentlessly - and yet now, it's all gone. And it's all thanks to Dupixent. I think I wanted to make this post to reaffirm hope. Hope in the fact that, as cruel as a condition this is, it will get better. I also think, while other conditions, like TSW, need to have awareness raised for - we also have to be mindful that eczema can just be severe sometimes. Keep using your medicines as prescribed, and it will get better. If anyone has any questions, let me know :) - UK based, so only able to provide advice and experience based on NHS guidelines.
  • what helped my eczema (detailed list)
    Sept. 29, 2024
    disclaimer: eczema is a very individual disease with different causes and triggers for every person. what works for me might not work for you and what didn’t work for me might work for you. just keep that in mind! though i do encourage trying out different things that are not steroids or medical prescription drugs, because the constellation of things can really change your eczema. first, what didn’t work for me and potentially also made it worse: - TOPICAL STEROIDS: when i was a child and first had eczema, the only thing doctors ever did was prescribe me topical steroids like advantan. though they did help a little bit in the moment, my eczema always came back, worse than before. that was going on for years until i developed TSW (tropical steroid withdrawal) when i was 18 years old and steroids stopped working entirely. i don’t think i have to say much about how horrible that was. steroids are only a short-term solution to a chronic illness. - GLUTEN FREE DIET: i also tried that one for longer but without success. that one is also particularly hard to do in a country where most food is based on gluten. - ELIDEL: when i was on dupixent, my facial flares were really bad. my doc said i should try this cream for a couple days a week. since its not a steroid, i was like okay, why not. but after a week with 3 appliances, my face started burning worse than before. i thought maybe i used it too much and tried it only one day a week, with nothing changing. - COCONUT OIL: though it did bring relief in some way, and it made me smell nice, it’s not a long term solution. it made the itching less, but just ended up making me feel gross and oily. also made my skin break out with pimples. and now, things that DID help me manage my eczema: - DUPIXENT: i have been on dupilumab since january and it helped me body recover from TSW. though now i am experiencing bad side effects and about to talk about stopping this treatment. nonetheless it can be a lifesaver for severe eczema. it brought me back from bad depression to being able to enjoy life again. - COLD SHOWERS: and i mean COLD showers. this one takes a lot of getting used to but helps SO much. less itching, less inflammation. EDIT: i’ve been lacking in doing this, especially because it’s so cold outside already. i have only been able to do lukewarm showers. i recommend starting a little warmer (not over bodyheat temperature) and then gradually decreasing the temperature. - REDUCE SUGAR INTAKE: i used to drink and eat a lot of industrial sugar. i love soda, i love chocolate and sweet snacks. but sadly i had to discover its bad influence on my eczema, since i got some bad itching-flashes after drinking or eating sugar. i only drink zero sugar soda now and try to eat less sweet snacks. - LOW DAIRY/SPICY FOODS: i still eat some dairy (like in coffee) but i try to do it less and less. dairy seems to be a big trigger for me. spicy foods are also well known to trigger eczema so i would recommend not eating too much chili-based foods. i specifically react to pepper/pepperoni/jalapeño’s. - ANTIHISTAMINES: you have to be careful with this one. there is some antihistamines you can take regularly, and some you shouldn’t. i take allegra almost every night to help with itching and redness. i record my allegra intake. definitely consult a doctor about this. - MICROFIBER TOWEL/BEDDING: since using this very soft but very breathable material for my bed i have less issues with overheating at night. it doesn’t snag and drag on the skin which is a lot less irritating than other materials. as a towel it doesn’t dry you off too much which initially can feel weird and useless, but i figured it helps with not stealing the moisture after showering and since i lotion immediately after showering, it locks water inside and leaves me feeling more moisturized. - TOPICAL ANTIFUNGALS: have helped me with side effects of dupixent. i used to get these really bad open wounds on my upper lip that just wouldn’t go away. used clotrimazol on it for 3 weeks and it was gone. - ZINK OXIDE CREAM: i know has been discussed a lot recently here. i use it every night before bed for all my sores. it relieves the itching, has antibacterial properties and due to the cream ingredients (vaseline) it locks moisture. it has greatly helped me with sores on my face. - SALT BATHS/BLEACHED POOLS: salt water baths helped me during the worst TSW episodes. though it was more of a temporary relief, it did help with the overwhelming shedding of dead skin. what helped more with the inflammation was bathing in pools with bleach, because i always felt a lot less itchy and open wounds would rather heal quickly. be sure to always moisturize after though. - SHEA BUTTER: I use a moisturizer with glycerin and shea butter at least twice daily. it’s the only one that has consistently worked making my skin feel less dry and not reacting to it after long time of usage (which has been happening with a lot of lotions/creams i
  • Dupixent saved my life… My eczema story
    Sept. 18, 2024
    **Hi everyone! In this post, I want to share my journey with eczema and my initial experiences with Dupixent. If you are only interested in my experience with Dupixent: Feel free to skip Part 1 and jump straight to Part 2!** **(PART 1)** I’ve suffered from eczema since a young age. Over the years, the problems shifted. As a child, I mainly had eczema in the creases of my arms and knees. Later, it appeared more on my hands, and I also developed respiratory issues (which are often correlated with eczema). Two years ago, my eczema became severe. It spread all over my body, including my face. The condition was so crippling that I couldn't sleep. I would go 3-4 days without sleep, reaching a point where I started experiencing hallucinations, and all I could think about was being freed from this miserable existence. (To be honest.. I just wanted to die and was extremely emotional drained during this time) As a child, I underwent multiple treatments—steroid creams, UVB therapy—but nothing provided long-lasting relief. Eventually, I ended up at a clinic outside of the hospital system. There, I received a course of prednisone (1 week), followed by cyclosporine (≈ 1 year). The cyclosporine had good effect, and I was able to gradually reduce the dosage after some months. However, my eczema flared up again, and even the maximum dose of cyclosporine couldn't control my symptoms. I was on this medication for about a year before being urgently referred to UMC Utrecht. Unfortunately, my new treatment was delayed last January due to a bacterial and viral infection in my throat. I suspect that the cyclosporine had weakened my natural immune system to the point that I suffered more than I should have. I was hospitalized, lost 15Kg (33 pounds) and ended up having to get my tonsils removed whilst they were still inflamed. I was left with a hole in my throat for several months as the healing process was slow. A few months before this happened, I met my girlfriend, who went through this difficult period with me. Unlike my previous dark times, having her by my side helped me tremendously. I will forever be grateful to her for this. Anyway, due to this setback, I was finally able to start my new treatment at UMC Utrecht in March, three months later than originally planned. **(PART 2)** UMC Utrecht is an academic hospital, and it was there that I started treatment with Dupixent. My experience with Dupixent has been life-changing (until now). I've been on the treatment for over six months now. My skin is still not perfect, but considering where I started, I’m not complaining! Your body needs time to adjust to the medication. I read on Reddit that some people saw results within a few weeks to three months. For me, it took longer—around five months before I started to notice improvement. There were ups and downs, and the waiting game was exhausting. Very exhausting. But in the past few weeks, I’ve finally started to see consistent positive results. I still sometimes combine Dupixent with steroid creams. Although I’m not a fan of these creams, they can be effective when used in combination with the Dupixent treatment (for me). Sometimes a short period of application can calm the skin when it gets irritated. Just make sure to follow a schedule provided by your doctor and never stop using the cream abruptly—I made that mistake before and ended up unable to sleep for days. For the people who never heard about this—This is called TSW “topical steroid withdrawal” and can be super painful. As for side effects, they have been minimal for me. In the beginning, I experienced burning sensations in my calves, and my eyes were constantly red or inflamed. The eye problems lasted for about 2-3 months. I'm sharing this because I know how hard it can be to deal with eczema. People’s reactions to my appearance bothered me the least; it was the mental toll that drained me. I’ve been through some very dark times. Now, I finally see a glimmer of hope, and I want to help others who might be in a similar situation. If you have any questions or want to share your experiences, feel free to reach out. I’ll do my best to respond to everyone. **Stay strong, everyone. Persistence pays off. Life can still show you its good sides.**
The medication is approved for patients 6 months and older with moderate-to-severe atopic dermatitis that is not well controlled with topical prescription treatments. Continuous treatment is needed to maintain response.
What does the research say?
Study Summary

In children aged 6 months to 6 years with moderate-to-severe eczema, dupilumab with low-strength steroid cream worked significantly better than placebo. After 16 weeks, 28% of children on dupilumab had clear or almost clear skin compared to only 4% on placebo, and 53% had major improvement in their eczema compared to 11% on placebo.

Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis: a randomised, double-blind, placebo-controlled, phase 3 trial
Study Type
Clinical Trial
Studied Population
Total Patients: 162
Severity: moderate to severe
Age: 6 months to <6 years
Results
Study Summary

This study showed that taking dupilumab every 2 weeks maintains improvements in eczema symptoms over 36 weeks. About 72% of patients maintained their improvement when taking dupilumab every 2 weeks, compared to only 30% of patients who stopped treatment. The study found that taking dupilumab less frequently (every 4 or 8 weeks) was not as effective as taking it every 2 weeks.

Efficacy and Safety of Multiple Dupilumab Dose Regimens After Initial Successful Treatment in Patients With Atopic Dermatitis
Study Type
Clinical Trial
Studied Population
Total Patients: 422
Results
What are other patients saying?
  • Steroids saved my skin
    April 20, 2024
    I’ve suffered from eczema my whole life (I’m 22) and I’d never used steroids before 3 weeks ago. I had heard so many horror stories of TSW and skin thinning so I avoided them. Over the past 3 years, my eczema has gotten worse on my neck and arms, which I’ve been managing by moisturising 3 times a day. My skin was always a bit itchy and I just put up with it. Until I started a new job a couple of weeks ago and the stress made my eczema flare SO badly, I couldn’t even turn my head because my neck hurt so much. It was flaking everywhere and I couldn’t wear dark coloured shirts because of the flakes (disgusting I know). It was so red, wet, and probably close to being infected. I’ve never flared so badly in my life. I was desperate so went to the pharmacy and the pharmacist gave me Novasone cream. It cleared my eczema in 4 days - I used the smallest amount of the cream once a day for 4 days - and my skin healed!!! It has been 3 weeks and my eczema still hasn’t returned!! I don’t even need moisturiser! So I wanted to write this post for anyone who was like me scared to try steroids, steroids are helpful for flare ups and breaking the cycle, just ensure to use them sparingly. I could’ve saved myself so many years of suffering had I known earlier! It feels so amazing to not be itchy!! UPDATE September 2024: This was very much a temporary solution indeed. My eczema was great for about a month after using the steroid but it came back again. Then I used the steroid again, and it cleared it up but came back a few weeks later. I repeated this cycle and my eczema came back more and more quickly, and now my eczema comes back 2 DAYS after stopping the steroid. Going to ask my dermatologist about going on Dupixent as my eczema is now all over my neck, face and arms and is the worst it has ever been and not healing.
  • Dupixent Made Me Cry
    Dec. 8, 2024
    Hello: I am writing to tell my story, hoping that it will help others. I suffered from horrific eczema for the first 26 years of life. The backs of knees, elbows, torso, lower back, legs, forearms, everywhere basically. It looked like I had a wrestling match against a cheese grater and lost. Badly. I had been to dermatologists, one of which said 99% of people outgrow eczema once puberty begins (the only 1% I'll ever be a member of). I had tried bleach baths to some relief, every topical steroid they make, an assortment of lotions, creams, and ointments. Nothing helped long-term. Tinkering with my diet didn't do much either. Then I fucked a dermatologist who said "oh, baby, you need help" when I took my clothes off. They asked for my pharmacy and then commanded me to go to their full-length mirror and photograph every inch of my body. They then said take those photos to a dermatologist Monday morning and ask for dupixent. So I did. I had to take an oral steroid for a bit due to insurance reasons (they want you to exhaust all cheap options first apparently). It was ineffective. Then they allowed my rx for dupixent. I took the loading dose which is two back-to-back injections. They send a nurse to your home to coach you through it. After I took the injections, nothing really happened at first. A few hours later though it happened. It all stopped. The constant, background burning sensation I felt around the clock halted. It was to my understanding that that was just the pain of existence, but I was wrong. There's a whole beautiful world out there, and I had finally stepped into it. It was like in the Wizard of Oz when Dorothy steps into color. I cannot recommend it enough to anyone that is out there still suffering. It took a few weeks but my skin did clear up entirely. I have minor scarring in my joints, but that's only if you really take a close look. I've never had a single thing improve my quality of life so dramatically before. It's been an incredible experience. God bless Dupixent.
  • Finally got Dupixent!
    Aug. 10, 2024
    Random happy post because I’m so glad to finally get this medicine. Eczema has cost me so much money and pain in all forms, and this medicine took 7 months to finally have. My insurance luckily covers it, otherwise there is NO way I could have afforded it. Hoping this helps my situation! UPDATE: I finally got the doses in and omg. It’s insane to finally be itch free. My dishydrotic eczema on my hands is gone and my face is actually clear. All that’s left physically are scars. I’m so grateful to be able to take this medicine. This actually might have changed my life. I have noticed side effects though! My doctor did tell me I might have eye issues but that hasn’t been a problem for me, but there are others I wasn’t told about. -loss of appetite -trouble sleeping Those are the most prevalent I’ve noticed so far. I’m up very late and wake up a lot throughout the night, and I have absolutely no appetite. I think both can be easily managed once I’m more used to it, I just have to make sure I’m staying within healthy ranges. Still, I am so grateful for the medicine and I really hope it holds throughout college as my dorms have allergens.
Is Dupixent Right For Me?
What is Dupixent?
Dupilumab (DUPIXENT) is a monoclonal antibody that works by blocking certain proteins (IL-4 and IL-13) that cause inflammation in the body. It is given as an injection under the skin.
What are the requirements for taking Dupixent?
Dupixent might be right for you if:

  • You are 6 months of age or older

  • You have moderate-to-severe atopic dermatitis

  • Your disease is not well controlled with prescription topical treatments

  • Topical treatments are not recommended for you

How does Dupixent work?
It works by blocking two specific proteins (interleukin-4 and interleukin-13) that drive inflammation in atopic dermatitis. By blocking these proteins, it helps reduce inflammation in the skin and relieves symptoms.
Is it safe for children?
Dupilumab is safe and effective for children 6 months of age and older with moderate-to-severe atopic dermatitis. The safety and effectiveness are generally similar between children and adults.
Is it safe for elderly patients?
Clinical trials included limited numbers of patients 65 years and older with atopic dermatitis. There is not enough data to determine if elderly patients respond differently from younger patients.
Is it safe during pregnancy?
Based on available data, dupilumab has not been linked to birth defects or other pregnancy problems. However, the medicine can cross the placenta from mother to baby. Discuss with your doctor if you are pregnant or planning to become pregnant.
Is it safe during breastfeeding?
It is not known if dupilumab passes into breast milk or what effects it might have on a breastfed baby. The benefits of breastfeeding and the mother's need for dupilumab should be considered along with any potential risks.