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Based on 25 studies
Side Effect | Affected |
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Highlights
- May improve symptoms in patients with low zinc levels
- Zinc-containing cream reduced symptoms by 74% in children after 6 weeks
- Can enhance effectiveness of steroid creams
- Steroid-free option available for children
- Generally well-tolerated with minimal side effects
Zinc levels are often lower in people with atopic dermatitis, and oral zinc supplements may help improve symptoms in patients who have low zinc levels. Improvements were seen in skin condition, itching, and sleep.
Study Summary | Study Type | Studied Population | Results |
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Children with atopic dermatitis had lower zinc levels in their hair compared to healthy children. When children with low zinc levels were given zinc supplements, their eczema symptoms, skin barrier function, and itching improved more than those who didn't receive supplements.
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Randomized Controlled Trial |
Total Patients: 58
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Zinc supplementation successfully increased hair zinc levels |
Children with atopic dermatitis had lower zinc levels in their hair compared to healthy children. When children with low zinc levels were given zinc supplements, their eczema symptoms, skin barrier function, and itching improved more than those who didn't receive supplements.
Hair zinc levels and the efficacy of oral zinc supplementation in patients with atopic dermatitisA cream containing zinc oxide along with other ingredients (starch, glycyrretinic acid, and bisabolol) was effective in treating mild-to-moderate atopic dermatitis in children, reducing symptoms by 74% after 6 weeks of use. This cream is steroid-free and was well-tolerated.
Study Summary | Study Type | Studied Population | Results |
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Not all studies show benefits of oral zinc supplements. One study found no improvement in eczema symptoms when children took zinc sulphate supplements for 8 weeks.
Study Summary | Study Type | Studied Population | Results |
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When combined with a steroid cream (Clobetasol), adding zinc sulphate improved the treatment's effectiveness for hand eczema and reduced the chance of the condition returning after treatment.
Study Summary | Study Type | Studied Population | Results |
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A combination cream containing Clobetasol and zinc sulphate was more effective in treating chronic hand eczema compared to Clobetasol alone. The combination treatment also showed lower recurrence rates of eczema after treatment.
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Randomized Controlled Trial |
Total Patients: 47
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Combination cream showed significantly better improvement in all measured symptoms and lower recurrence rates compared to Clobetasol alone |
A combination cream containing Clobetasol and zinc sulphate was more effective in treating chronic hand eczema compared to Clobetasol alone. The combination treatment also showed lower recurrence rates of eczema after treatment.
The efficacy of '0.05% Clobetasol + 2.5% zinc sulphate' cream vs. '0.05% Clobetasol alone' cream in the treatment of the chronic hand eczema: a double-blind studyIs Zinc Right For Me?
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You have irritated or chafed skin
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You need protection from moisture
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You have minor skin irritation
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You have diaper rash (for babies)
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How Lemma Health Works
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Fill out a 3 minute questionnaire to find evidence-based treatments that work for you.
Meet your provider
Consult with a board-certified dermatologist. Discuss your treatment options and receive prescriptions.
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Your journey with lemma health
Discover effective treatments with board‑certified dermatologists.
Get prescriptions for immediate relief.
Get your medications.
Design a plan for sustained relief with your personal care coordinator.
Experience less itch, reduced inflammation, better sleep, and improved wellbeing.
Review progress with your care team and fine-tune your plan.
Ensure that you have everything you need to maintain your relief.
Don't worry - your coordinator will remain available to you.
Enjoy 24/7/365 access to your dedicated care team.
Discover effective treatments with board‑certified dermatologists.
Get prescriptions for immediate relief.
Get your medications.
Design a plan for sustained relief with your personal care coordinator.
Experience less itch, reduced inflammation, better sleep, and improved wellbeing.
Enjoy 24/7/365 access to your dedicated care team.
Ensure that you have everything you need to maintain your relief.
Don't worry - your coordinator will remain available to you.
Review progress with your care team and fine-tune your plan.
Illustrative journey. Individual timelines and results may vary.

Ready for better skin health?
At Lemma Health, we provide evidence-based skin care. Access dermatologists in all 50 states - appointments available within 3 days. Receive your medications delivered. Message your dedicated care team 24/7/365.
What are others saying?
The following comments are sourced from publicly available forums, including Reddit. They reflect personal opinions and anecdotal experiences, and do not constitute medical advice. Lemma Health does not verify the accuracy, completeness, or authorship of these statements, nor does it endorse any specific treatment, medication, or outcome mentioned. These excerpts are provided for informational purposes only.
Since I started doing this, the eczema on my thighs has virtually disappeared (some hyper pigmented areas remain but the skin is smooth and just slightly dry). For the first time in almost 2 years I actually have clear skin on my thighs.
View SourceBut when I put bacitracin, which targets bacteria instead of fungus, I had huge monumental symptom relief. It's like 90% better, the cracking peeling and inflammation all stopped. My skin felt like normal skin to the touch.
View SourceWe collect reviews of treatments from various sources including social media and are not always able to verify whether these have been written by actual patients.