Omega-3 (polyunsaturated fatty acid)
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How well does Omega-3 work?
Omega-3 is below average for atopic dermatitis "Supplements and Natural Remedies" treatments.
What is the evidence behind Omega-3?
The effectiveness of fish oil supplements for eczema may depend on genetics. In pregnant women with a specific genetic type (TT genotype), taking fish oil during pregnancy reduced their children's risk of developing eczema. However, for women with different genetic types, it either had no effect or could increase the risk.
What does the research say?
Study Summary

This study looked at whether taking fish oil supplements during pregnancy could prevent eczema in children. The effectiveness depended on the mother's genes - it helped prevent eczema in children whose mothers had a specific genetic type (TT genotype) but increased the risk in mothers with a different genetic type (CC genotype).

Prenatal Fish Oil Supplementation, Maternal COX1 Genotype, and Childhood Atopic Dermatitis: A Secondary Analysis of a Randomized Clinical Trial.
Study Type
Randomized Controlled Trial
Studied Population
Total Patients: 635
Severity: not available
Age: 0-10 years
Results
No overall effect on AD risk when not considering genetic differences

What are other patients saying?
  • If you haven’t already try Omega-3 supplements!!
    May 27, 2023
    I saw a post here at some point that talked about omega 3 helping… didn’t think much of it but i started taking it just to see and there really is a big difference. I stopped taking it again because i assumed it was a fluke and my eczema was so so much worse within a week of not taking it. For reference I have moderate eczema that affects basically my whole body. I’ve been taking Jamieson brand 1000 mg Omega-3 Softgels (Fish oil). Either 2 or 4 a day - i think the higher dose works better but I rarely remember to take it in the morning and 2 helps too. 2 is the recommended dose. Just thought i’d make a post to spread the word a bit in case there’s some people here who haven’t tried it yet! Not saying it will work for you, but i hope it will!!
  • Omega 3 making skin worst
    June 16, 2024
    Has Omega 3 made anyone skin worst? I've tried numerous brand, like store brands up to strong ones like Carlson's and Nordic naturals but it makes me super itchy and my skin even more dry. I look like a mummy sometimes.
  • Omega 3 fatty acid supplement for eczema
    Dec. 27, 2023
    I was researching about supplements the other day and stumbled upon an article which says omega 3 supplement is effective in reducing the inflammation. Has anyone tried fish oil supplements and have they worked? I suffer from lips eczema which has gotten worse during this dry season. I have ordered omega 3 supplements and hoping to see some relief.
When combined with gamma-linolenic acid (GLA) and vitamin D, fish oil supplements showed promising results in children with eczema, reducing symptom severity, itching, and the need for steroid creams. It also improved sleep quality and overall quality of life.
What does the research say?
Study Summary

Children with eczema who took omega-3 supplements combined with GLA from blackcurrant seed oil showed significant improvement in their symptoms after 4 months. The treatment reduced skin inflammation, itching, and the need for steroid creams by about half.

Effect of Omega-3 Polyunsaturated Fatty Acid Supplementation on Clinical Outcome of Atopic Dermatitis in Children
Study Type
Randomized Controlled Trial
Studied Population
Total Patients: 52
Severity: moderate to severe
Age: children
Results

What are other patients saying?
  • Been taking omega 3 for less than a week…
    Aug. 29, 2023
    And my mild eczema on my neck is going away! At first I thought it was in my head but my itching redness is going away… I’ve been taking 2000mg daily for less than a week and already see significant improvement. Mind you, my eczema is pretty mild and only flares up every few years when my immune system/overall health is depressed. Just wanted to share my experience, hoping it might help. Thanks!
  • Research: Reduce 22% or 15% autoimmune by taking Vitamin D3 or Omega-3
    April 6, 2024
    Hi y'all, If you haven't already, please take Vitamin D3 & Omega 3 to reduce your symptom. Easier to read: [https://news.harvard.edu/gazette/story/2022/01/vitamin-d-reduced-rate-of-autoimmune-diseases-by-22/](https://news.harvard.edu/gazette/story/2022/01/vitamin-d-reduced-rate-of-autoimmune-diseases-by-22/) The link to the research paper itself: [https://www.bmj.com/content/376/bmj-2021-066452](https://www.bmj.com/content/376/bmj-2021-066452) The easier to understand explanation can be found by this youtuber from minute 8:45 ish to minute 19th : [https://www.youtube.com/watch?v=TlKDpY9nqgs](https://www.youtube.com/watch?v=TlKDpY9nqgs) During the double blinded research, they were using 2000 IU Vitamin D3 & 1gm Fish Oil(Ethyl Ester form) & they see this improvement. If you never get your Vitamin D checked, please do it if you can. Of course other factors like dietary&lifestyle play important role, but if this improve my situation by 10% that is much better than getting my symptom get worse.
  • Dealing With Massive Eczema Scars :(
    Jan. 10, 2025
    **TLDR** ; I have severe toilet seat dermatitis which leaves my whole buttocks and thighs with patchy brown scars, and I also have some eczema scar spots on my forehead/torso. Any dietary/topical product recommendations? Hi everyone! (*I'm posting for the second time here, tqsm for those who responded previously, I owe you a lot!!*) So I've scrolled through the subreddit and been looking whether there have been anyone sharing their struggles with fading massive eczema scars over their body. I could say that I live with eczema within three phase ; 10y/o - 13y/o (moderately severe), 19y/o - 21 y/o (just random flares) and now, 23 y/o - 25 y/o (absolutely severe). It first started when my country (South East Asia, tropical climate) hit by heatwaves which the weather severely triggers my eczema. Long story short, it makes me have red flares all over my body, and over the time, endless scratching leaves huge scars on my torso. And at some random point of my life, I get myself toilet seat dermatitis due to frequent usage of office toilet during my internship, which ruins my buttocks and thighs so bad :(( The flares are already under control with the help from the steroid cream, but I wonder can I slowly take any measures to fade away the scars? I do some reading based on my local health page, and most sources cited these things helpful to deal with the scars : l-glutathione, fish oil supplements (as it contains Omega-3 and -6), and some powerful antioxidant supplement such as berries-based products. Could anyone that have similar experience kindly share about your journey of dealing with the eczema
Taking fish oil supplements during pregnancy and early breastfeeding (up to 6 months after birth) did not show clear benefits in preventing allergic conditions, including eczema, in children up to age 2.
What does the research say?
Study Summary

Taking fish oil and/or probiotics during pregnancy and up to 6 months after giving birth did not reduce the risk of atopic eczema or food allergies in children up to 2 years of age. Probiotics alone did reduce the risk of recurring wheezing in 2-year-olds.

Maternal fish oil and/or probiotics intervention: Allergic diseases in children up to two years old
Study Type
Randomized Controlled Trial
Studied Population
Total Patients: 439
Severity: not available
Age: 0-2 years
Results
No benefit of fish oil and/or probiotics in preventing atopic eczema

What are other patients saying?
  • High dose omega 3 EPA/DHA - can someone explain
    April 20, 2022
    Like lots of people on here, I’ve tried almost everything to get rid of my eczema/seb derm. I recently saw someone saying that you don’t get any benefits from Omega 3 till you take a high dose of it. So I upped my dose from 500mg DHA/EPA to around 3000mg DHA/EPA and my skin has healed and all my triggers have stopped triggering me including mould, dust, foods. How is this possible and can someone explain how the high dose of Omega 3 can somewhat subdue my allergies and allow my eczema to heal? Does this mean I was Omega 3 deficient? I’m stumped by how well and simple it has been to reduce it. Thanks
  • Omega 3 Fish Oils Side Effects
    March 31, 2020
    Hello, I just started taking 4,000 mg if Omega 3 Fish Oils for eczema and have noticed better skin already! However, I feel like I’m getting hot flashes. Slight sweating, etc. Has anyone noticed similar side effects? Gonna try taking one 2,000 mg pill instead of the two.
  • Intermittent fasting caused me to experience severe eczema
    Aug. 23, 2024
    Hi all, happy Friday. I just wanted to share my own personal experience with eczema. When it comes to my health, I'm pretty proactive and health-conscious and I've always been the type of person who likes to look for the root cause rather than use medication to mask symptoms. I'm also a scientist - so naturally, I love reading about the mechanisms behind adequate health and wellness. So I don't like using steroids because long-term use isn't safe and they mask symptoms, but I will use them when my symptoms are unbearable like they recently were. I'm 29 and have had eczema for 9 years. Thankfully it's mostly on my hands and is very manageable (occasional flareup usually when it's cold and dry outside or humid and muggy or when I'm stressed or when I was my hands too much). There are so many root causes of eczema, and I've done a lot of personal research on myself. Mine is caused by genetics and hormone imbalances (I had my first flare at puberty) and it worsens with stress. I have borderline high cortisol. So I put on weight last year and wanted to find a way to lose it. I decided to do 16-8 intermittent fasting. I lost a lot of weight, though unfortunately 3 weeks into my fasting I developed a horrible flare. My skin has been itchy, dry, swollen, inflamed, and bloody for months and it has never been this bad despite having mild/moderate eczema beforehand. This was so unbearable. I could not work some days and had to go to urgent care. I could not go a week without steroid creams and had to get a steroid shot and prednisone pills, which elevated my blood sugar (not eczema related but still concerning). I developed inflammation on certain areas of my skin that were otherwise healthy and not impacted beforehand (wrists, neck, ears, and face). I quit fasting and started to eat a piece of fruit in the morning. Since I started doing this, my skin slowly started to heal. It's not 100%, but I have not needed to use steroid creams in a while and my skin looks great for skin that hasn't been treated with steroids in some time. I'm so hopeful and feel much better. I'm convinced I put a lot of stress on my body with fasting, which manifested as severe eczema, hormone imbalances, as well as fatigue. I also developed rashes and staph/fungal infections. Last time I had skin inflammation and infections of this severity was when I was on a strict diet in college. So it all made sense to me when I made the connection. I'm so happy I have my skin and energy back. I wanted to bring this to your attention because it shows that prolonged stress on your body (doesn't have to be mental stress, but any stressor like longterm dieting) can cause inflammation and therefore eczema. I was recently reading that women shouldn't be fasting for too long because of our hormone cycling which can cause imbalances and inflammation. This is something worth looking into if you're someone who is experiencing stress, lack of sleep/disrupted circadian rhythm, dieting and restriction, and female hormone imbalances. I've done so much personal research and testing when it comes to eczema, like allergy testing, gut health, nutrients, stress relief, heavy metals, and now hormone imbalances (which I would have never thought would be linked to eczema, but that's definitely one of my root causes besides genetics). As I read more about hormones, I really hope my skin improves even more. I take zinc, vitamin D, and omega-3 fatty acids and have not seen much improvement with them. I also follow an anti-inflammatory diet and have previously taken some supplements to help with my gut (minor improvement). I've seen some improvements with my diet, but the best improvements when I quit fasting. I hope this educates you in some way if you're experiencing something similar.
Is Omega-3 Right For Me?
What is Omega-3?
Omega-3 is a supplement that contains essential fatty acids, primarily EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), which are derived from fish oil.
What are the requirements for taking Omega-3?
Omega-3 might be right for you if:
  • You are an adult

  • You have very high triglyceride levels (500 mg/dL or higher)

  • You are already following a healthy diet to lower your triglycerides

How does Omega-3 work?
Omega-3 works in several ways to help lower triglycerides (a type of fat) in your blood. It reduces the production of triglycerides in your liver and helps break down fats in your body. While the exact mechanism isn't fully understood, it helps improve your body's fat metabolism.
Is it safe for children?
Safety and effectiveness in children have not been established.
Is it safe for elderly patients?
Limited studies have been done in people over 65, but current evidence suggests it's as safe and effective in older adults as it is in younger adults.
Is it safe during pregnancy?
While there isn't enough human data to determine all risks, animal studies suggest Omega-3 is generally safe during pregnancy when taken at recommended doses. However, you should discuss use with your healthcare provider.
Is it safe during breastfeeding?
Omega-3 fatty acids can pass into breast milk. While this isn't necessarily harmful (and may be beneficial), you should discuss use with your healthcare provider during breastfeeding.