Zyrtec Product Details

Zyrtec (cetirizine)

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Highlights

Reduces itching and skin symptoms in all age groups
Safe for long-term use, including in young children
Can reduce need for strong topical steroids
May help prevent asthma in allergic children
May cause drowsiness and dry mouth

How well does Zyrtec work?

Zyrtec is above average for atopic dermatitis "Over-the-Counter Medicines" treatments.

What is the evidence behind Zyrtec?

Cetirizine is effective at reducing itching and other skin symptoms in both children and adults with atopic dermatitis

What does the research say?

Study Summary	Study Type	Studied Population	Results
📄 Cetirizine helped reduce itching and other symptoms of atopic dermatitis in adults, with better results at higher doses (40mg). The medication was most effective at reducing itching, redness, and skin thickening compared to placebo. Dose ranging study: cetirizine in the treatment of atopic dermatitis in adults	Clinical Trial	Total Patients: 178 Severity: not available Age: 18+	Higher doses of cetirizine were more effective at improving symptoms, with 40mg showing the best results

Study Summary

Cetirizine helped reduce itching and other symptoms of atopic dermatitis in adults, with better results at higher doses (40mg). The medication was most effective at reducing itching, redness, and skin thickening compared to placebo.

Dose ranging study: cetirizine in the treatment of atopic dermatitis in adults

Study Type

Clinical Trial

Studied Population

Total Patients: 178

Severity: not available

Age: 18+

Results

Higher doses of cetirizine were more effective at improving symptoms, with 40mg showing the best results

What are other patients saying?

Long-term use of cetirizine is safe, even in young children. Studies showed no negative effects on behavior, thinking ability, or physical development when used for up to 18 months

What does the research say?

Study Summary	Study Type	Studied Population	Results
📄 Cetirizine was found to be safe for long-term use in young children with atopic dermatitis. The medication showed similar or fewer side effects compared to placebo over 18 months of treatment. Prospective, long-term safety evaluation of the H1-receptor antagonist cetirizine in very young children with atopic dermatitis. ETAC Study Group. Early Treatment of the Atopic Child	Clinical Trial	Total Patients: 817 Severity: not available Age: 12-24 months	This was primarily a safety study

Study Summary

Cetirizine was found to be safe for long-term use in young children with atopic dermatitis. The medication showed similar or fewer side effects compared to placebo over 18 months of treatment.

Prospective, long-term safety evaluation of the H1-receptor antagonist cetirizine in very young children with atopic dermatitis. ETAC Study Group. Early Treatment of the Atopic Child

Study Type

Clinical Trial

Studied Population

Total Patients: 817

Severity: not available

Age: 12-24 months

Results

This was primarily a safety study

What are other patients saying?

Cetirizine can help reduce the need for strong topical steroids in patients with moderate-to-severe atopic dermatitis

What does the research say?

Study Summary	Study Type	Studied Population	Results
📄 Long-term use of cetirizine in infants with atopic dermatitis helped reduce the need for stronger topical steroids, especially in patients with more severe disease. The medication also significantly reduced the occurrence of hives compared to placebo (5.8% vs 16.2%). Long-term treatment with cetirizine of infants with atopic dermatitis: a multi-country, double-blind, randomized, placebo-controlled trial (the ETAC trial) over 18 months	Clinical Trial	Total Patients: 817 Severity: not specified Age: 12-24 months

Study Summary

Long-term use of cetirizine in infants with atopic dermatitis helped reduce the need for stronger topical steroids, especially in patients with more severe disease. The medication also significantly reduced the occurrence of hives compared to placebo (5.8% vs 16.2%).

Long-term treatment with cetirizine of infants with atopic dermatitis: a multi-country, double-blind, randomized, placebo-controlled trial (the ETAC trial) over 18 months

Study Type

Clinical Trial

Studied Population

Total Patients: 817

Severity: not specified

Age: 12-24 months

Results

What are other patients saying?

In children with atopic dermatitis who are allergic to grass pollen or dust mites, cetirizine may help prevent or delay the development of asthma

What does the research say?

Study Summary	Study Type	Studied Population	Results
📄 In infants with atopic dermatitis who were allergic to grass pollen or house dust mites, cetirizine treatment for 18 months helped prevent or delay the development of asthma. This protective effect was particularly strong and lasted for 36 months in children allergic to grass pollen. A double-blinded, randomized, placebo-controlled trial of cetirizine in preventing the onset of asthma in children with atopic dermatitis: 18 months' treatment and 18 months' posttreatment follow-up	Clinical Trial	Severity: not available Age: 1-2 years	Cetirizine prevented/delayed asthma development in sensitized infants

Study Summary

In infants with atopic dermatitis who were allergic to grass pollen or house dust mites, cetirizine treatment for 18 months helped prevent or delay the development of asthma. This protective effect was particularly strong and lasted for 36 months in children allergic to grass pollen.

A double-blinded, randomized, placebo-controlled trial of cetirizine in preventing the onset of asthma in children with atopic dermatitis: 18 months' treatment and 18 months' posttreatment follow-up

Study Type

Clinical Trial

Studied Population

Severity: not available

Age: 1-2 years

Results

Cetirizine prevented/delayed asthma development in sensitized infants

What are other patients saying?

Is Zyrtec Right For Me?

Cetirizine is an antihistamine medication that helps relieve allergy symptoms like itching, sneezing, and runny nose. It's available over-the-counter and comes in tablet form.

Zyrtec might be right for you if:

You are 6 years or older
You have allergy symptoms like itching, sneezing, or runny nose
You have symptoms from hay fever or other upper respiratory allergies

Cetirizine works by blocking histamine, a natural substance in your body that causes allergy symptoms. When histamine is blocked, you experience less itching, sneezing, and other allergy symptoms.

Safe for children 6 years and older at appropriate doses. For children under 6 years, consult with a doctor before use.

Adults 65 years and older should consult with a doctor before use. Dose adjustments may be needed, especially if there are kidney problems.

Limited data available. Consult with your healthcare provider before using cetirizine during pregnancy.

Cetirizine passes into breast milk. Consult with your healthcare provider before using while breastfeeding.

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How Lemma Health Works

Discover effective treatments

Fill out a 3 minute questionnaire to find evidence-based treatments that work for you.

Meet your provider

Consult with a board-certified dermatologist. Discuss your treatment options and receive prescriptions.

Get treatment

Treatments are delivered to your door. Free of charge, of course.

Receive ongoing care

Your treatment team is available 7 days a week for questions, support, and guidance.

Ready?

Your journey with lemma health

Today

Discover effective treatments with board‑certified dermatologists.

Get prescriptions for immediate relief.

Within a week

Get your medications.

Design a plan for sustained relief with your personal care coordinator.

2-4 weeks

Experience less itch, reduced inflammation, better sleep, and improved wellbeing.

4–6 weeks

Review progress with your care team and fine-tune your plan.

3 months

Ensure that you have everything you need to maintain your relief.

Don't worry - your coordinator will remain available to you.

Always

Enjoy 24/7/365 access to your dedicated care team.

Today

Discover effective treatments with board‑certified dermatologists.

Get prescriptions for immediate relief.

Within a week

Get your medications.

Design a plan for sustained relief with your personal care coordinator.

2-4 weeks

Experience less itch, reduced inflammation, better sleep, and improved wellbeing.

Always

Enjoy 24/7/365 access to your dedicated care team.

3 months

Ensure that you have everything you need to maintain your relief.

Don't worry - your coordinator will remain available to you.

4–6 weeks

Review progress with your care team and fine-tune your plan.

Illustrative journey. Individual timelines and results may vary.

Ready for better skin health?

At Lemma Health, we provide evidence-based skin care. Access dermatologists in all 50 states - appointments available within 3 days. Receive your medications delivered. Message your dedicated care team 24/7/365.