Explore Other Treatments
Highlights
- Shows significant improvement in 2-4 weeks
- 96% of patients tolerate treatment well
- 70% of patients stay relapse-free with maintenance therapy
- Mild effects in about 4% of patients
- Available in multiple forms (cream, lotion, ointment)
Clobetasol propionate is a highly effective treatment for eczema, with studies showing significant improvement in symptoms like redness, itching, and inflammation within 2-4 weeks of treatment
| Study Summary | Study Type | Studied Population | Results |
|---|---|---|---|
|
📄
Clobetasol propionate cream 0.05% was tested against a vehicle (cream without active ingredient) in patients with moderate-to-severe atopic dermatitis. The study lasted 4 weeks with twice daily application.
|
Clinical Trial |
Total Patients: 81
|
|
|
📄
Clobetasol cream was more effective than fluocinonide cream in treating eczema when applied three times daily for 2 weeks. Clobetasol showed faster healing and fewer side effects (4%) compared to fluocinonide (12%).
|
Clinical Trial |
Total Patients: 113
Severity: not available Age: adolescent and adult
|
Clobetasol showed faster healing and maintained efficacy, while fluocinonide's healing rate slowed after first week |
Clobetasol propionate cream 0.05% was tested against a vehicle (cream without active ingredient) in patients with moderate-to-severe atopic dermatitis. The study lasted 4 weeks with twice daily application.
Clobetasol propionate emollient 0.05% in the treatment of atopic dermatitisClobetasol cream was more effective than fluocinonide cream in treating eczema when applied three times daily for 2 weeks. Clobetasol showed faster healing and fewer side effects (4%) compared to fluocinonide (12%).
Clobetasol propionate versus fluocinonide creams in psoriasis and eczemaThe medication can be safely used with minimal side effects when used as directed. Side effects, when they occur, are generally mild and affect about 4% of patients
| Study Summary | Study Type | Studied Population | Results |
|---|---|---|---|
|
📄
Clobetasol cream was more effective than fluocinonide cream in treating eczema when applied three times daily for 2 weeks. Clobetasol showed faster healing and fewer side effects (4%) compared to fluocinonide (12%).
|
Clinical Trial |
Total Patients: 113
Severity: not available Age: adolescent and adult
|
Clobetasol showed faster healing and maintained efficacy, while fluocinonide's healing rate slowed after first week |
|
📄
Clobetasol propionate, a very strong topical steroid, was more effective than flupredniden acetate (medium strength steroid) in preventing hand eczema from coming back. When using clobetasol twice weekly, 70% of patients remained free from eczema flares compared to 30% with flupredniden.
|
Clinical Trial |
Total Patients: 55
|
Clobetasol was more effective at preventing relapses than flupredniden |
Clobetasol cream was more effective than fluocinonide cream in treating eczema when applied three times daily for 2 weeks. Clobetasol showed faster healing and fewer side effects (4%) compared to fluocinonide (12%).
Clobetasol propionate versus fluocinonide creams in psoriasis and eczemaClobetasol propionate, a very strong topical steroid, was more effective than flupredniden acetate (medium strength steroid) in preventing hand eczema from coming back. When using clobetasol twice weekly, 70% of patients remained free from eczema flares compared to 30% with flupredniden.
Intermittent maintenance therapy in chronic hand eczema with clobetasol propionate and flupredniden acetateUsing clobetasol propionate twice weekly as maintenance therapy can help prevent relapses in chronic eczema, with studies showing it kept 70% of patients free from relapses during the observation period
| Study Summary | Study Type | Studied Population | Results |
|---|---|---|---|
|
📄
Clobetasol propionate, a very strong topical steroid, was more effective than flupredniden acetate (medium strength steroid) in preventing hand eczema from coming back. When using clobetasol twice weekly, 70% of patients remained free from eczema flares compared to 30% with flupredniden.
|
Clinical Trial |
Total Patients: 55
|
Clobetasol was more effective at preventing relapses than flupredniden |
Clobetasol propionate, a very strong topical steroid, was more effective than flupredniden acetate (medium strength steroid) in preventing hand eczema from coming back. When using clobetasol twice weekly, 70% of patients remained free from eczema flares compared to 30% with flupredniden.
Intermittent maintenance therapy in chronic hand eczema with clobetasol propionate and flupredniden acetateThe medication comes in different forms (cream, lotion, ointment) with similar effectiveness, though the lotion form may provide better long-term results after stopping treatment
| Study Summary | Study Type | Studied Population | Results |
|---|
Clobetasol propionate is highly effective at treating eczema, with success rates of over 90% in multiple studies. It typically starts working within a few days and can clear symptoms within 2-4 weeks of treatment.
| Study Summary | Study Type | Studied Population | Results |
|---|---|---|---|
|
📄
Clobetasol propionate emollient cream 0.05% was tested against a placebo cream in patients with moderate-to-severe atopic dermatitis. The study lasted 4 weeks with twice daily application.
|
Clinical Trial |
Total Patients: 81
Severity: moderate to severe Age: ≥12 years
|
not available |
Clobetasol propionate emollient cream 0.05% was tested against a placebo cream in patients with moderate-to-severe atopic dermatitis. The study lasted 4 weeks with twice daily application.
Clobetasol propionate emollient 0.05% in the treatment of atopic dermatitisWhen used twice weekly for maintenance therapy, clobetasol can help prevent eczema from coming back. In one study, 70% of patients remained free from relapses using this approach.
| Study Summary | Study Type | Studied Population | Results |
|---|---|---|---|
|
📄
Clobetasol propionate (a very strong steroid) was more effective than flupredniden acetate (a medium-strength steroid) in preventing hand eczema from coming back. When using clobetasol twice weekly, 70% of patients remained free from eczema flares compared to 30% with flupredniden.
|
Clinical Trial |
Total Patients: 55
|
Clobetasol was more effective at preventing relapses when used twice weekly |
Clobetasol propionate (a very strong steroid) was more effective than flupredniden acetate (a medium-strength steroid) in preventing hand eczema from coming back. When using clobetasol twice weekly, 70% of patients remained free from eczema flares compared to 30% with flupredniden.
Intermittent maintenance therapy in chronic hand eczema with clobetasol propionate and flupredniden acetateWhile generally safe for short-term use, side effects can occur in about 4% of patients. These are usually mild but can include skin thinning and temporary changes in cortisol levels. Regular monitoring by a doctor is recommended for long-term use.
| Study Summary | Study Type | Studied Population | Results |
|---|---|---|---|
|
📄
Clobetasol cream was more effective than fluocinonide cream in treating eczema when applied three times daily for 2 weeks. Clobetasol showed faster healing and fewer side effects (4%) compared to fluocinonide (12%).
|
Clinical Trial |
Total Patients: 113
Severity: not available Age: adolescent and adult
|
Clobetasol showed faster healing and maintained efficacy, while fluocinonide's healing rate slowed after first week |
|
📄
Clobetasol propionate emollient cream 0.05% was tested against a placebo cream in patients with moderate-to-severe atopic dermatitis. The study lasted 4 weeks with twice daily application.
|
Clinical Trial |
Total Patients: 81
Severity: moderate to severe Age: ≥12 years
|
not available |
Clobetasol cream was more effective than fluocinonide cream in treating eczema when applied three times daily for 2 weeks. Clobetasol showed faster healing and fewer side effects (4%) compared to fluocinonide (12%).
Clobetasol propionate versus fluocinonide creams in psoriasis and eczemaClobetasol propionate emollient cream 0.05% was tested against a placebo cream in patients with moderate-to-severe atopic dermatitis. The study lasted 4 weeks with twice daily application.
Clobetasol propionate emollient 0.05% in the treatment of atopic dermatitisDifferent formulations (cream, lotion, emollient) appear to be similarly effective, though some studies suggest the lotion form may provide better long-term results than the cream version.
| Study Summary | Study Type | Studied Population | Results |
|---|
Is Clobetasol Right For Me?
-
You are 12 years or older
-
You have inflammation or itching from a skin condition that responds to steroids
-
You need short-term treatment (up to 2 weeks)
-
Your condition requires a very strong steroid
Interested in eczema products?
As a member of the Lemma Health community, you'll stay up to date with research, hear about new products, and get exclusive access to discounts.
How Lemma Health Works
Discover effective treatments
Fill out a 3 minute questionnaire to find evidence-based treatments that work for you.
Meet your provider
Consult with a board-certified dermatologist. Discuss your treatment options and receive prescriptions.
Get treatment
Treatments are delivered to your door. Free of charge, of course.
Receive ongoing care
Your treatment team is available 7 days a week for questions, support, and guidance.
Ready?
Your journey with lemma health
Discover effective treatments with board‑certified dermatologists.
Get prescriptions for immediate relief.
Get your medications.
Design a plan for sustained relief with your personal care coordinator.
Experience less itch, reduced inflammation, better sleep, and improved wellbeing.
Review progress with your care team and fine-tune your plan.
Ensure that you have everything you need to maintain your relief.
Don't worry - your coordinator will remain available to you.
Enjoy 24/7/365 access to your dedicated care team.
Discover effective treatments with board‑certified dermatologists.
Get prescriptions for immediate relief.
Get your medications.
Design a plan for sustained relief with your personal care coordinator.
Experience less itch, reduced inflammation, better sleep, and improved wellbeing.
Enjoy 24/7/365 access to your dedicated care team.
Ensure that you have everything you need to maintain your relief.
Don't worry - your coordinator will remain available to you.
Review progress with your care team and fine-tune your plan.
Illustrative journey. Individual timelines and results may vary.
Ready for better skin health?
At Lemma Health, we provide evidence-based skin care. Access dermatologists in all 50 states - appointments available within 3 days. Receive your medications delivered. Message your dedicated care team 24/7/365.
Eczema is more than skin deep
Join our waitlist while we set up personalized holistic eczema care.
What are other patients saying?
He prescribed a topical steroid cream (Clobetasol propionate) and a disinfectant antifungal antibacterial bath (potassium permanganate) to cover both scenarios and I used them for a week (2x per day for steroid) — it worked miraculously well (Pic 2). [...] I accidentally skipped a day, then went to 1x a day, and that's when my healed smooth hand started to develop little bumps.
View SourceAfter using it daily, the patch did disappear and and a redness colour remained. If I'm honest I'd pick the discolouration over the actual eczema any day. [...] It has now been a week since I stopped and my eczema has appeared again.
View Source2 weeks into clobetasol and it didnt work. It may have worked to smoothed out the skin, but it is still inflamed as hell. This has never happened to me before, my eczema always responed well to clobetasol.
View Source