Clobetasol propionate versus fluocinonide creams in psoriasis and eczema

B Jegasothy, C Jacobson, N Levine, L Millikan, E Olsen, S Pinnell, G Cole, G Weinstein, M Porter

Clinical Trial

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113 participants

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1985

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4 citations

Key insights related to Clobetasol from this study:

What is this paper about?

This paper compares two steroid creams (clobetasol propionate and fluocinonide) to see which works better for treating psoriasis and eczema. The study looked at how well each cream worked and how safe they were.
How did the authors study this?

The researchers conducted a double-blind study where patients applied either clobetasol or fluocinonide cream three times daily for 2 weeks. They evaluated the results through doctors' assessments, measurement of specific symptoms, and patients' own reports of improvement.
What populations did the authors study?

The study included 113 patients with eczema and 114 with psoriasis who were adolescents and adults. No specific information was provided about disease severity or prior treatments.
What conclusions can we draw?

The authors concluded that clobetasol propionate cream was more effective than fluocinonide for treating both eczema and psoriasis. Both treatments were considered safe, though clobetasol had fewer side effects than fluocinonide.

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