This paper examines whether vitamin D supplementation can help reduce the severity of atopic dermatitis. The researchers looked at how vitamin D levels relate to atopic dermatitis severity and whether supplementation could improve symptoms.

The researchers conducted a pre-post intervention study where they measured vitamin D levels and atopic dermatitis severity (using SCORAD) in patients. Those with low vitamin D levels received supplements for 3 months, after which they were reassessed. They also performed skin prick tests on all patients.

The study included 152 patients under 14 years of age with atopic dermatitis. The patients were categorized based on their vitamin D levels (sufficient, insufficient, or deficient) and their atopic dermatitis severity (mild, moderate, or severe).

Patients with sufficient vitamin D levels had less severe atopic dermatitis. After 3 months of supplementation, vitamin D levels increased significantly (from 23.7 to 35.9 ng/mL), and the severity of atopic dermatitis decreased (SCORAD decreased from 19.4 to 12.3). Female patients showed a worse response to the treatment.

The authors conclude that vitamin D supplementation could be helpful as an additional treatment to reduce the severity of atopic dermatitis.