(3.67)
Based on 13 studies
Side Effect | Affected |
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diarrhea | |
nausea |

Highlights
- 74% of patients see improvement
- Works as well as oral antibiotics
- Easy to apply directly on skin
- Mild effects like diarrhea and nausea
- Bacteria may return after stopping treatment
Mupirocin combined with steroid creams (like hydrocortisone or fluticasone) is effective and safe for treating atopic dermatitis, especially when there might be bacterial infection present. In one study, 74% of patients improved with this combination treatment.
Study Summary | Study Type | Studied Population | Results |
---|---|---|---|
đź“„
Using hydrocortisone cream combined with mupirocin was more effective (74% success) than hydrocortisone alone (65% success) or moisturizer (36% success) in treating mild to moderate atopic dermatitis in infants. The combination treatment was safe and helped address potential bacterial infection.
|
Randomized Controlled Trial |
Total Patients: 83
|
Combined treatment with hydrocortisone and mupirocin was most effective, followed by hydrocortisone alone, both significantly better than emollient |
đź“„
A combination ointment containing fluticasone propionate and mupirocin was effective in treating atopic dermatitis with suspected bacterial infection. After 2 weeks of treatment, the majority of patients (67.2%) had only mild disease, and patient comfort improved from 33.65% to 78.60%.
|
Clinical Trial |
Total Patients: 122
Severity: mild to severe Age: not available
|
Significant improvement in disease severity with majority of patients achieving mild disease status |
Using hydrocortisone cream combined with mupirocin was more effective (74% success) than hydrocortisone alone (65% success) or moisturizer (36% success) in treating mild to moderate atopic dermatitis in infants. The combination treatment was safe and helped address potential bacterial infection.
Hydrocortisone acetate alone or combined with mupirocin for atopic dermatitis in infants under two years of age - a randomized double blind pilot trialA combination ointment containing fluticasone propionate and mupirocin was effective in treating atopic dermatitis with suspected bacterial infection. After 2 weeks of treatment, the majority of patients (67.2%) had only mild disease, and patient comfort improved from 33.65% to 78.60%.
Efficacy and safety of combination ointment "fluticasone propionate 0.005% plus mupirocin 2.0%" for the treatment of atopic dermatitis with clinical suspicion of secondary bacterial infection: an open label uncontrolled studyMupirocin cream is as effective as oral antibiotics (like cephalexin) for treating infected eczema, with fewer side effects. It's also preferred by patients because it's applied directly to the skin rather than taken as pills.
Study Summary | Study Type | Studied Population | Results |
---|---|---|---|
đź“„
Mupirocin cream was found to be as effective as oral cephalexin (an antibiotic) for treating infected eczema. The cream worked better at killing bacteria and was preferred by patients over taking oral medication.
|
Clinical Trial |
Total Patients: 159
Severity: secondarily infected eczema Age: not available
|
Mupirocin cream was similarly effective to oral cephalexin |
Mupirocin cream was found to be as effective as oral cephalexin (an antibiotic) for treating infected eczema. The cream worked better at killing bacteria and was preferred by patients over taking oral medication.
A comparison of the efficacy and safety of mupirocin cream and cephalexin in the treatment of secondarily infected eczemaWhile mupirocin can effectively reduce bacteria (particularly Staphylococcus aureus) on the skin during treatment, bacteria levels may return to normal after stopping treatment. However, this doesn't necessarily mean symptoms will get worse.
Study Summary | Study Type | Studied Population | Results |
---|---|---|---|
đź“„
Mupirocin, a topical antibiotic, significantly reduced Staphylococcus aureus bacteria on the skin of atopic dermatitis patients and improved their symptoms. Although bacteria returned after stopping treatment, patients' symptoms didn't get worse during the study period.
|
Clinical Trial |
Total Patients: 49
Severity: not available Age: not available
|
Mupirocin significantly reduced bacterial counts |
Mupirocin, a topical antibiotic, significantly reduced Staphylococcus aureus bacteria on the skin of atopic dermatitis patients and improved their symptoms. Although bacteria returned after stopping treatment, patients' symptoms didn't get worse during the study period.
Staphylococcal colonization in atopic dermatitis and the effect of topical mupirocin therapyShort-term use of mupirocin appears to be safe, with minimal side effects. The most common side effects reported were mild and included diarrhea and nausea.
Study Summary | Study Type | Studied Population | Results |
---|---|---|---|
đź“„
Mupirocin cream was found to be as effective as oral cephalexin (an antibiotic) for treating infected eczema. The cream worked better at killing bacteria and was preferred by patients over taking oral medication.
|
Clinical Trial |
Total Patients: 159
Severity: secondarily infected eczema Age: not available
|
Mupirocin cream was similarly effective to oral cephalexin |
đź“„
Mupirocin, a topical antibiotic, significantly reduced Staphylococcus aureus bacteria on the skin of atopic dermatitis patients and improved their symptoms. Although bacteria returned after stopping treatment, patients' symptoms didn't get worse during the study period.
|
Clinical Trial |
Total Patients: 49
Severity: not available Age: not available
|
Mupirocin significantly reduced bacterial counts |
Mupirocin cream was found to be as effective as oral cephalexin (an antibiotic) for treating infected eczema. The cream worked better at killing bacteria and was preferred by patients over taking oral medication.
A comparison of the efficacy and safety of mupirocin cream and cephalexin in the treatment of secondarily infected eczemaMupirocin, a topical antibiotic, significantly reduced Staphylococcus aureus bacteria on the skin of atopic dermatitis patients and improved their symptoms. Although bacteria returned after stopping treatment, patients' symptoms didn't get worse during the study period.
Staphylococcal colonization in atopic dermatitis and the effect of topical mupirocin therapyIs Mupirocin Right For Me?
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You have impetigo (a bacterial skin infection)
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Your infection is caused by specific bacteria (Staphylococcus aureus or Streptococcus pyogenes)
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You need a topical (on the skin) treatment
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Don't worry - your coordinator will remain available to you.
Enjoy 24/7/365 access to your dedicated care team.
Discover effective treatments with board‑certified dermatologists.
Get prescriptions for immediate relief.
Get your medications.
Design a plan for sustained relief with your personal care coordinator.
Experience less itch, reduced inflammation, better sleep, and improved wellbeing.
Enjoy 24/7/365 access to your dedicated care team.
Ensure that you have everything you need to maintain your relief.
Don't worry - your coordinator will remain available to you.
Review progress with your care team and fine-tune your plan.
Illustrative journey. Individual timelines and results may vary.

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What are others saying?
I started testing out different products that were capable of clearing the Staph and I came across a cream called Mupider. I have been applying this cream once a day (at night, right after bathing) and it has totally eased up my eczema (close to no itch).
View SourceWe collect reviews of treatments from various sources including social media and are not always able to verify whether these have been written by actual patients.