This paper studies whether a vitamin B12-containing barrier cream works better than a standard moisturizing cream for treating mild atopic dermatitis. The researchers compared these two treatments directly against each other.
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Superiority of a vitamin B12‐barrier cream compared with standard glycerol‐petrolatum‐based emollient cream in the treatment of atopic dermatitis: A randomized, left‐to‐right comparative trial
Superiority of a vitamin B12‐barrier cream compared with standard glycerol‐petrolatum‐based emollient cream in the treatment of atopic dermatitis: A randomized, left‐to‐right comparative trial
S P Nistico, E Del Duca, F Tamburi, E Pignataro, N De Carvalho, F Farnetani, G Pellacani
DOI: 10.1111/dth.12523
Randomized Controlled Trial
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22 participants
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2017
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7 citations
Key insights related to Vitamin B12 from this study:
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What is this paper about?
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How did the authors study this?
The researchers conducted a single-blind trial where patients applied vitamin B12 cream to one side of their body and standard moisturizing cream to the other side. They used the SCORAD index (a measure of eczema severity) to track improvements over 4 months, with patients applying the creams three times daily.
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What populations did the authors study?
The study included 22 patients with mild atopic dermatitis.
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What did the authors find?
After 12 weeks, the areas treated with vitamin B12 cream showed a 77.6% reduction in SCORAD (eczema severity), while areas treated with standard moisturizer showed only a 33.5% reduction.
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What conclusions can we draw?
The authors conclude that vitamin B12 cream could be a new treatment option for mild atopic dermatitis, as it performed better than standard moisturizing cream.
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