A cohort study on the risk of lymphoma and skin cancer in users of topical tacrolimus, pimecrolimus, and corticosteroids (Joint European Longitudinal Lymphoma and Skin Cancer Evaluation – JOELLE study)

TBD

DOI: 10.2147/CLEP.S146442

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• What is this paper about?

  People using tacrolimus or pimecrolimus creams for eczema had a slightly higher risk of developing lymphoma compared to those using corticosteroid creams, but the actual number of cases was very small, suggesting minimal risk for individual patients.

• How did the authors study this?

  Study conclusions are drawn from an observational study. Observational studies is a research method where researchers measure differences between different groups. The study is not as strong as a randomized controlled study since it can be prone to selection bias and confounding factors.

• What populations did the authors study?

  Children and adults using topical tacrolimus, pimecrolimus, or corticosteroids

• What did the authors find?

  Lymphoma incidence: Number of new lymphoma cases per 100,000 person-years
  Skin cancer incidence: Number of new skin cancer cases per 100,000 person-years