Halobetasol (halobetasol propionate)
Effectiveness:

(4.39)

Based on 7 studies

Side Effects:
Medium

Image for illustration purposes only. Actual medication may appear different.

Topical
Daily
Available by Prescription
As Low as $

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Highlights

  • Success rates of 88-94% in treating eczema
  • Fast-acting with improvements seen within 3 days
  • Highly effective when used as cream/ointment combination
  • Low rate of side effects (2-5% of patients)
  • Can cause skin dryness, itching, or burning at application site
  • Potential for skin thinning with prolonged use

What are others saying?

No reviews available yet

We collect reviews of treatments from various sources including social media and are not always able to verify whether these have been written by actual patients.


How well does Halobetasol work?
Halobetasol is above average for atopic dermatitis "Steroids" treatments.
What is the evidence behind Halobetasol?
Halobetasol is highly effective at treating eczema, with success rates between 88-94% across multiple studies. Most patients see significant improvement or complete healing of their eczema.
What does the research say?
Study Summary

Halobetasol propionate cream was as effective as two other steroid creams (clobetasol and betamethasone) in treating severe atopic dermatitis. About 88-93% of patients showed significant improvement, with effects starting within 3 days for about 40% of patients.

Double-blind, comparative clinical trials with halobetasol propionate cream in patients with atopic dermatitis
Study Type
Clinical Trial
Studied Population
Total Patients: 264
Severity: severe
Age: Not specified
Results
All three treatments showed similar high success rates

Study Summary

Halobetasol propionate ointment was more effective than diflucortolone valerate ointment in treating severe atopic dermatitis, with 91.5% of patients showing significant improvement compared to 83.6%. It also worked faster, with 70% of patients seeing improvements within 3 days, and had fewer side effects.

A double-blind, multicenter, parallel-group trial with 0.05% halobetasol propionate ointment versus 0.1% diflucortolone valerate ointment in patients with severe, chronic atopic dermatitis or lichen simplex chronicus
Study Type
Clinical Trial
Studied Population
Total Patients: 120
Results
Halobetasol propionate showed better overall success rate

What are others saying?
The medication works quickly, with many patients seeing improvements within the first 3 days of treatment. This fast action makes it particularly useful for quick relief of symptoms.
What does the research say?
Study Summary

Halobetasol propionate ointment was more effective than diflucortolone valerate ointment in treating severe atopic dermatitis, with 91.5% of patients showing significant improvement compared to 83.6%. It also worked faster, with 70% of patients seeing improvements within 3 days, and had fewer side effects.

A double-blind, multicenter, parallel-group trial with 0.05% halobetasol propionate ointment versus 0.1% diflucortolone valerate ointment in patients with severe, chronic atopic dermatitis or lichen simplex chronicus
Study Type
Clinical Trial
Studied Population
Total Patients: 120
Results
Halobetasol propionate showed better overall success rate

Study Summary

Halobetasol propionate 0.05% ointment was significantly more effective than vehicle (placebo) in treating eczema. After 2 weeks of treatment, 83% of patients using halobetasol showed complete or marked improvement compared to 28% using vehicle. The medication was well-tolerated with no skin thinning reported.

A review of two controlled multicenter trials comparing 0.05% halobetasol propionate ointment to its vehicle in the treatment of chronic eczematous dermatoses
Study Type
Clinical Trial
Studied Population
Total Patients: 224
Results
Halobetasol was significantly more effective than vehicle in treating chronic eczema

What are others saying?
Halobetasol is generally safe and well-tolerated. Side effects are uncommon (occurring in only 2-5% of patients) and usually mild, mainly including skin dryness, itching, or burning sensations at the application site.
What does the research say?
Study Summary

Halobetasol propionate cream was as effective as two other steroid creams (clobetasol and betamethasone) in treating severe atopic dermatitis. About 88-93% of patients showed significant improvement, with effects starting within 3 days for about 40% of patients.

Double-blind, comparative clinical trials with halobetasol propionate cream in patients with atopic dermatitis
Study Type
Clinical Trial
Studied Population
Total Patients: 264
Severity: severe
Age: Not specified
Results
All three treatments showed similar high success rates

Study Summary

Halobetasol propionate cream 0.05% was significantly more effective than placebo in treating atopic dermatitis symptoms when applied twice daily for 14 days. The cream improved itching, redness, scaling, and thickened skin, with benefits seen within 7 days of treatment.

Double-blind bilateral paired comparison of 0.05% halobetasol propionate cream and its vehicle in patients with chronic atopic dermatitis and other eczematous dermatoses
Study Type
Clinical Trial
Studied Population
Total Patients: 111
Severity: Chronic
Age: Not specified
Results
Significant improvement in all symptoms compared to vehicle (p<0.001)

What are others saying?
The medication is available in both cream and ointment forms, and can be effective in both adults and children. In pediatric patients, it showed excellent results with 100% success rate for eczema treatment.
What does the research say?
Study Summary

Halobetasol propionate cream was as effective as two other steroid creams (clobetasol and betamethasone) in treating severe atopic dermatitis. About 88-93% of patients showed significant improvement, with effects starting within 3 days for about 40% of patients.

Double-blind, comparative clinical trials with halobetasol propionate cream in patients with atopic dermatitis
Study Type
Clinical Trial
Studied Population
Total Patients: 264
Severity: severe
Age: Not specified
Results
All three treatments showed similar high success rates

What are others saying?
Halobetasol propionate is highly effective at treating eczema, with success rates (defined as 'healed' or 'marked improvement') ranging from 88% to 94% in various studies. It starts working quickly, with many patients seeing improvement within 3 days of starting treatment.
What does the research say?
Study Summary

Halobetasol propionate cream was found to be as effective as two other steroid creams (clobetasol and betamethasone) in treating severe atopic dermatitis. About 88-90% of patients showed significant improvement, with effects starting within 3 days for about 40% of patients.

Double-blind, comparative clinical trials with halobetasol propionate cream in patients with atopic dermatitis
Study Type
Clinical Trial
Studied Population
Total Patients: 264
Severity: severe
Age: Not available
Results
All three treatments showed similar high effectiveness

Study Summary

Halobetasol propionate ointment was more effective than diflucortolone valerate ointment in treating severe atopic dermatitis, with 91.5% of patients showing significant improvement compared to 83.6%. It also worked faster, with 70% of patients seeing improvements within 3 days, and had fewer side effects.

A double-blind, multicenter, parallel-group trial with 0.05% halobetasol propionate ointment versus 0.1% diflucortolone valerate ointment in patients with severe, chronic atopic dermatitis or lichen simplex chronicus
Study Type
Clinical Trial
Studied Population
Total Patients: 120
Results
Halobetasol propionate showed better overall success rate

What are others saying?
The medication is generally well-tolerated with a low rate of side effects (2-5% of patients). The most common side effects are skin dryness, itching, or burning at the application site.
What does the research say?
Study Summary

Halobetasol propionate cream was found to be as effective as two other steroid creams (clobetasol and betamethasone) in treating severe atopic dermatitis. About 88-90% of patients showed significant improvement, with effects starting within 3 days for about 40% of patients.

Double-blind, comparative clinical trials with halobetasol propionate cream in patients with atopic dermatitis
Study Type
Clinical Trial
Studied Population
Total Patients: 264
Severity: severe
Age: Not available
Results
All three treatments showed similar high effectiveness

Study Summary

Halobetasol propionate cream 0.05% was significantly more effective than placebo in treating atopic dermatitis symptoms when applied twice daily for 14 days. The medication improved itching, redness, scaling, and thickened skin, with benefits seen within 7 days of treatment.

Double-blind bilateral paired comparison of 0.05% halobetasol propionate cream and its vehicle in patients with chronic atopic dermatitis and other eczematous dermatoses
Study Type
Clinical Trial
Studied Population
Total Patients: 111
Results
Significant improvement in all symptoms compared to vehicle by day 7 and day 14 (p<0.001)

What are others saying?
In children with severe eczema, the combination of halobetasol propionate cream during the day and ointment at night was extremely effective, with a 100% success rate. However, careful monitoring is needed as one case of mild skin thinning was reported.
What does the research say?
What are others saying?
The medication performs as well as or better than other strong topical steroids like clobetasol propionate and betamethasone dipropionate, making it a reliable option for treating severe eczema.
What does the research say?
Study Summary

Halobetasol propionate cream was found to be as effective as two other steroid creams (clobetasol and betamethasone) in treating severe atopic dermatitis. About 88-90% of patients showed significant improvement, with effects starting within 3 days for about 40% of patients.

Double-blind, comparative clinical trials with halobetasol propionate cream in patients with atopic dermatitis
Study Type
Clinical Trial
Studied Population
Total Patients: 264
Severity: severe
Age: Not available
Results
All three treatments showed similar high effectiveness

Study Summary

Halobetasol propionate ointment was more effective than diflucortolone valerate ointment in treating severe atopic dermatitis, with 91.5% of patients showing significant improvement compared to 83.6%. It also worked faster, with 70% of patients seeing improvements within 3 days, and had fewer side effects.

A double-blind, multicenter, parallel-group trial with 0.05% halobetasol propionate ointment versus 0.1% diflucortolone valerate ointment in patients with severe, chronic atopic dermatitis or lichen simplex chronicus
Study Type
Clinical Trial
Studied Population
Total Patients: 120
Results
Halobetasol propionate showed better overall success rate

What are others saying?

Is Halobetasol Right For Me?

Halobetasol propionate is a super-high potency topical corticosteroid (steroid cream) that helps reduce inflammation and itching in skin conditions.
Halobetasol might be right for you if:
  • You have inflammatory skin conditions that respond to corticosteroids

  • You are 12 years or older

  • You need treatment for no longer than 2 weeks

  • You will not use more than 50g per week

It works by reducing inflammation, redness, and itching in the skin. It belongs to a class of medications called corticosteroids, which help calm down the immune system's response in the skin.
Not recommended for children under 12 years old. Children are at higher risk of side effects because they absorb more of the medication through their skin relative to their body size.
Can be used in elderly patients. Clinical studies showed no overall differences in safety or effectiveness between older and younger patients, though some older individuals might be more sensitive to the medicine.
This medicine is Pregnancy Category C, which means it should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. Animal studies have shown some risks, but there aren't adequate studies in pregnant women.
Unknown

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