Desonide Product Details

Desonide (desonide)

Available Online

Topical

Daily

Available by Prescription

As Low as $

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Highlights

Shows significant improvement in 1-2 weeks
Up to 100% effective when combined with moisturizers
Safe for children and infants
Helps prevent disease recurrence for up to 69 days
Minimal impact on body's natural hormone production

How well does Desonide work?

Desonide is above average for atopic dermatitis "Steroids" treatments.

What is the evidence behind Desonide?

Desonide is effective at treating atopic dermatitis, with studies showing significant improvements in symptoms like itching and inflammation. When combined with moisturizers, it shows even better results with up to 100% effectiveness compared to 60% with desonide alone.

What does the research say?

Study Summary	Study Type	Studied Population	Results

What are other patients saying?

Desonide is particularly safe for children, including infants. Studies show it rarely affects the body's natural hormone (cortisol) production, making it safer than stronger steroids like betamethasone.

What does the research say?

Study Summary	Study Type	Studied Population	Results
📄 Desonide hydrogel 0.05%, a low-potency steroid, was found to be safe and effective in treating children aged 6 months to 6 years with moderate-to-severe atopic dermatitis. The treatment showed good results in improving symptoms while having minimal impact on the body's hormone system. Effect of desonide hydrogel 0.05% on the hypothalamic-pituitary-adrenal axis in pediatric subjects with moderate to severe atopic dermatitis	Clinical Trial	Total Patients: 40 Severity: moderate to severe Age: 6 months-6 years	Treatment was generally safe with minimal impact on the body's hormone system
📄 Both desonide 0.05% ointment and hydrocortisone 2.5% ointment were found to be safe for children with atopic dermatitis when used for 4 weeks. Neither medication affected the body's natural cortisol production system. Effect of desonide ointment, 0.05%, on the hypothalamic-pituitary-adrenal axis of children with atopic dermatitis	Clinical Trial		Both medications were safe for use in children and did not affect their natural cortisol production system
📄 Both desonide cream 0.1% and betamethasone cream were equally effective in treating childhood atopic dermatitis. However, desonide had less impact on the body's cortisol levels, making it potentially safer for children. [Comparative study of efficacy and effect on plasma cortisol levels of micronised desonide cream 0.1 p. 100 versus betamethasone dipropionate cream 0.05 p. 100 In the treatment of childhood atopic dermatitis]	Clinical Trial	Total Patients: 29 Severity: Not specified Age: mean 13.8 months	Both treatments showed similar clinical effectiveness

Study Summary

Desonide hydrogel 0.05%, a low-potency steroid, was found to be safe and effective in treating children aged 6 months to 6 years with moderate-to-severe atopic dermatitis. The treatment showed good results in improving symptoms while having minimal impact on the body's hormone system.

Effect of desonide hydrogel 0.05% on the hypothalamic-pituitary-adrenal axis in pediatric subjects with moderate to severe atopic dermatitis

Study Type

Clinical Trial

Studied Population

Total Patients: 40

Severity: moderate to severe

Age: 6 months-6 years

Results

Treatment was generally safe with minimal impact on the body's hormone system

Study Summary

Both desonide 0.05% ointment and hydrocortisone 2.5% ointment were found to be safe for children with atopic dermatitis when used for 4 weeks. Neither medication affected the body's natural cortisol production system.

Effect of desonide ointment, 0.05%, on the hypothalamic-pituitary-adrenal axis of children with atopic dermatitis

Study Type

Clinical Trial

Studied Population

Results

Both medications were safe for use in children and did not affect their natural cortisol production system

Study Summary

Both desonide cream 0.1% and betamethasone cream were equally effective in treating childhood atopic dermatitis. However, desonide had less impact on the body's cortisol levels, making it potentially safer for children.

[Comparative study of efficacy and effect on plasma cortisol levels of micronised desonide cream 0.1 p. 100 versus betamethasone dipropionate cream 0.05 p. 100 In the treatment of childhood atopic dermatitis]

Study Type

Clinical Trial

Studied Population

Total Patients: 29

Severity: Not specified

Age: mean 13.8 months

Results

Both treatments showed similar clinical effectiveness

What are other patients saying?

The hydrogel form of desonide helps improve skin moisture and barrier function, with significant improvements seen in as little as 1-2 weeks of treatment.

What does the research say?

Study Summary	Study Type	Studied Population	Results
📄 Desonide hydrogel 0.05% was found to be safe and effective in treating mild to moderate atopic dermatitis in children aged 3 months to 18 years. The treatment was well-tolerated and showed significant improvements compared to the vehicle (gel without medication). Safety and efficacy of desonide hydrogel 0.05% in pediatric subjects with atopic dermatitis	Clinical Trial	Total Patients: 582	The medication showed significant improvement compared to the vehicle alone

Study Summary

Desonide hydrogel 0.05% was found to be safe and effective in treating mild to moderate atopic dermatitis in children aged 3 months to 18 years. The treatment was well-tolerated and showed significant improvements compared to the vehicle (gel without medication).

Safety and efficacy of desonide hydrogel 0.05% in pediatric subjects with atopic dermatitis

Study Type

Clinical Trial

Studied Population

Total Patients: 582

Results

The medication showed significant improvement compared to the vehicle alone

What are other patients saying?

When used with moisturizers, desonide can help prevent disease recurrence. Studies show this combination can extend the time before symptoms return to about 69 days compared to 49 days with desonide alone.

What does the research say?

Study Summary	Study Type	Studied Population	Results

What are other patients saying?

Is Desonide Right For Me?

Desonide is a low-potency topical corticosteroid cream that comes as a 0.05% preparation. It belongs to the steroid family of medications that are applied directly to the skin.

Desonide might be right for you if:

You have a skin condition that responds to corticosteroids
You need short-term treatment (up to 2 weeks)
You don't need to use occlusive dressings

Desonide works by reducing inflammation, redness, and itching in the skin. It does this by suppressing the body's immune response in the affected area.

Safety and effectiveness in children have not been established. Children may be at higher risk of side effects because they absorb more of the medication through their skin relative to their body size. Serious side effects have been reported in children including growth problems, delayed weight gain, and high pressure in the brain.

Unknown

Use with caution. There are no adequate studies in pregnant women. Should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. Animal studies with similar medications have shown some risks.

Unknown

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Your journey with lemma health

Today

Discover effective treatments with board‑certified dermatologists.

Get prescriptions for immediate relief.

Within a week

Get your medications.

Design a plan for sustained relief with your personal care coordinator.

2-4 weeks

Experience less itch, reduced inflammation, better sleep, and improved wellbeing.

4–6 weeks

Review progress with your care team and fine-tune your plan.

3 months

Ensure that you have everything you need to maintain your relief.

Don't worry - your coordinator will remain available to you.

Always

Enjoy 24/7/365 access to your dedicated care team.

Today

Discover effective treatments with board‑certified dermatologists.

Get prescriptions for immediate relief.

Within a week

Get your medications.

Design a plan for sustained relief with your personal care coordinator.

2-4 weeks

Experience less itch, reduced inflammation, better sleep, and improved wellbeing.

Always

Enjoy 24/7/365 access to your dedicated care team.

3 months

Ensure that you have everything you need to maintain your relief.

Don't worry - your coordinator will remain available to you.

4–6 weeks

Review progress with your care team and fine-tune your plan.

Illustrative journey. Individual timelines and results may vary.

Ready for better skin health?

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