Allegra (fexofenadine)
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Highlights

  • Reduces itching within 1 day
  • Works both day and night
  • Decreases area of affected skin
  • Very mild, similar to placebo

What are other patients saying?

I have recently started taking fexofenadine antihistamines and quercetin supplements, alongside using natural moisturisers (think Shea butter, coconut oil ect ect.) [...] this is the first time in 20 months I haven't felt constantly miserable about my skin.

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How well does Allegra work?
Allegra is below average for atopic dermatitis "Over-the-Counter Medicines" treatments.
What is the evidence behind Allegra?
When combined with topical corticosteroids, fexofenadine significantly reduces itching (pruritus) in people with atopic dermatitis. The improvement in itching can be noticed after just 1 day of treatment.
What does the research say?
Study Summary

Adding fexofenadine (an antihistamine) to topical hydrocortisone helped reduce itching in patients with atopic dermatitis more effectively than hydrocortisone alone. The improvement in itching was seen after just 1 day of treatment and continued throughout the study week.

Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study
Study Type
Clinical Trial
Studied Population
Total Patients: 400
Severity: not available
Age: 16+
Results
Fexofenadine significantly reduced itching compared to placebo, with improvements seen after 1 day and maintained throughout the week

What are other patients saying?
Fexofenadine helps reduce itching both during the day and at night, and can decrease the area of skin affected by itching.
What does the research say?
Study Summary

Adding fexofenadine (an antihistamine) to topical hydrocortisone helped reduce itching in patients with atopic dermatitis more effectively than hydrocortisone alone. The improvement in itching was seen after just 1 day of treatment and continued throughout the study week.

Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study
Study Type
Clinical Trial
Studied Population
Total Patients: 400
Severity: not available
Age: 16+
Results
Fexofenadine significantly reduced itching compared to placebo, with improvements seen after 1 day and maintained throughout the week

What are other patients saying?
Fexofenadine is generally safe to use, with side effects similar to those experienced by people taking a placebo (sugar pill).
What does the research say?
Study Summary

Adding fexofenadine (an antihistamine) to topical hydrocortisone helped reduce itching in patients with atopic dermatitis more effectively than hydrocortisone alone. The improvement in itching was seen after just 1 day of treatment and continued throughout the study week.

Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study
Study Type
Clinical Trial
Studied Population
Total Patients: 400
Severity: not available
Age: 16+
Results
Fexofenadine significantly reduced itching compared to placebo, with improvements seen after 1 day and maintained throughout the week

What are other patients saying?

Is Allegra Right For Me?

Fexofenadine is an antihistamine medication that helps reduce allergic symptoms. It's available over-the-counter and is commonly known by brand names like Allegra.
Allegra might be right for you if:
  • You are 12 years or older

  • You have itching due to hives

  • You need relief from allergic symptoms

Fexofenadine works by blocking histamine, a natural substance in your body that causes allergic symptoms. By blocking histamine, it helps reduce itching and other allergic reactions.
Not recommended for children under 12 years of age. Children 12 years and older can take one 180 mg tablet daily.
Adults 65 years and older should consult with their doctor before using this medication.
Unknown - Consult with your healthcare provider before using during pregnancy.
Unknown - Consult with your healthcare provider before using while breastfeeding.

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2-4 weeks

Experience less itch, reduced inflammation, better sleep, and improved wellbeing.

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4–6 weeks

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